The mitotic spindle is the apparatus upon which chromosomes are segregated during cell division. We have discovered new roles for two members of the NIMA-related kinase (NEK) family in different molecular processes of spindle assembly. Moreover, loss of these proteins leads to segregation errors that drive cancer progression.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4909405PMC
http://dx.doi.org/10.1080/23723556.2015.1062952DOI Listing

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