Ependymomas are common spinal lesions, with the vast majority arising in an intramedullary location. Several cases have been described in the literature of ependymomas in an intradural, extramedullary location. The authors present a case of a 56-year-old female who presented with several weeks of lower back pain and weakness. MRI revealed an intradural, extramedullary enhancing mass at L1-L2. The mass was successfully resected surgically. Pathologic evaluation revealed a low grade glioma with components of both ependymoma and pilocytic astrocytoma with MUTYH G382D mutation. Extramedullary ependymomas are very rare tumors. To the authors' knowledge, this is the first case of ependymoma/astrocytoma collision tumors described in an extramedullary location.
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http://dx.doi.org/10.1155/2016/3534791 | DOI Listing |
Brain Sci
January 2025
Centre of Medical Sciences, Jan and Jędrzej Śniadeccy University of Science and Technology, 85-796 Bydgoszcz, Poland.
Background/objectives: While most studies on the postoperative condition of patients with spinal cord tumors describe long-term outcomes, data are needed on immediate surgical outcomes demanding rehabilitation to make informed assessments for postoperative planning. The aim of this study was to identify factors predicting function and rehabilitative needs after intradural spinal tumor surgery.
Methods: Eighty-five prospectively recruited patients underwent surgery for intradural intramedullary (ID-IM; = 23) and extramedullary (ID-EM; = 62) tumors.
Radiol Case Rep
March 2025
University of Baghdad, College of Medicine, Baghdad, Iraq.
Intradural extramedullary spinal cord tumors are rare but can cause significant neurological symptoms. We present a case of a 23-year-old male who developed progressive bilateral leg pain and lower limb weakness 2 years after undergoing posterior spinal fixation for a T12 burst fracture. Magnetic resonance imaging (MRI) revealed an intradural extramedullary tumor at the site of the previous surgery.
View Article and Find Full Text PDFCancers (Basel)
December 2024
Neurosurgery Department, Santa Maria delle Grazie Hospital, ASL Napoli 2 Nord, Via Domitiana Località La Schiana Pozzuoli, 80078 Naples, Italy.
Background: Although its validity has recently been questioned since its introduction, the Simpson grade has remained one of the most relevant factors in estimating the recurrence risk of intracranial meningiomas. This study aims to assess its role in spinal meningiomas through a retrospective analysis of a mono-institutional surgical series and literature meta-analysis.
Methods: We conducted a systematic review and meta-analysis of the literature from 1980 to 2023, complemented by a mono-institutional series of 74 patients treated at "Santa Maria delle Grazie" hospital.
Medicine (Baltimore)
January 2025
Department of Pathology, Deyang Peoples' Hospital, Deyang, Sichuan Province, China.
Rationale: Ependymomas are commonly prevalent intramedullary neoplasms in adults, with hardly any cases of exophytic extramedullary ependymoma being reported. Meningiomas, on the contrary, are one of the most common intradural extramedullary (IDEM) tumors. However, the occurrence of both IDEM tumors simultaneously is extremely rare.
View Article and Find Full Text PDFCureus
December 2024
Department of Neurology, International University of Health and Welfare Narita Hospital, Narita, JPN.
( gene rearrangement-positive small-cell lung cancer (SCLC) is extremely rare. A 73-year-old man was diagnosed with SCLC. Standard treatments were not effective.
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