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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894365PMC

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Diabetic foot wounds (DFW) are notoriously difficult to treat owing to poor vascularity, delayed healing and higher rates of infection. Human-derived acellular dermal matrices (ADM) have been used in DFW treatment, utilizing a matrix scaffold for new tissue generation. We investigate the efficacy of a micronized injectable human-derived ADM in the treatment of DFW.

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 Dermal substitutes offer a valuable tool in soft-tissue reconstruction, reducing the need for donor site tissue and its associated complications. However, conventional approaches often require multiple surgeries. This study aimed to compare the effectiveness of a single-stage procedure combining dermal substitute and skin grafting with hyperbaric oxygen (HBO) therapy to the standard multistage protocol.

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The reconstruction of full-thickness scalp defects with exposed bone can be challenging. A single-stage reconstruction could be the preferred option for patients with multiple comorbidities. We propose using a dermal regeneration template (Matriderm Flex) and full-thickness skin grafts.

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Background: Immediate breast reconstruction (IBR) with direct to implant (DTI) is the preferred method of reconstruction by many surgeons and patients, however, acellular dermal matrix (ADM) and other synthetic meshes are expensive especially in low- and middle-income countries. AIM OF THE WORK: To evaluate the technique, indications, aesthetic outcomes, and short and long-term complications of DTI breast reconstruction performed with Ultrapro®, a low-cost alternative mesh to ADM and other synthetic meshes.

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One-stage scalp reconstruction using single-layer dermal regeneration template and split-thickness skin graft: a case series.

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Multidisciplinary Department of Medical-Surgical and Dental Specialties. Oral and Maxillofacial Surgery Unit, University of Campania "Luigi Vanvitelli", Naples, 80138, Italy.

Article Synopsis
  • This study looks at a new way to fix scalp problems after surgery for skin cancer, which can be tough due to the scalp's unique structure.
  • Researchers analyzed patients treated with a special skin template and grafting between January 2020 and October 2023.
  • The results showed that most patients healed well and could start other cancer treatments quickly, making this method a good choice for scalp surgery.
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