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Extraventricular neurocytoma in the left temporal lobe: A case report and review of the literature. | LitMetric

Extraventricular neurocytoma in the left temporal lobe: A case report and review of the literature.

Oncol Lett

Department of Neurosurgery, Tsinghua University Yuquan Hospital, Beijing 100040, P.R. China; Medical Center, Tsinghua University, Beijing 100084, P.R. China.

Published: June 2016

Central neurocytoma (CNC) often develops in the ventricular system adjacent to the interventricular foramen and septum pellucidum. According to the World Health Organization, CNCs are classified as grade II tumors, and in recent years it has been reported that CNCs have occasionally occurred in rare areas of the central nervous system. The current study describes a rare case of CNC located in the left temporal lobe of a 49-year-old man, who had been experiencing headaches for 3 weeks. Computed tomography identified a round, well-demarcated, 3.3-cm tumor in the left temporal lobe. The patient underwent surgery and the tumor was totally resected. Histological analysis demonstrated that the resected tumor tissue contained clusters of small cells with regular nuclear morphology, and round nuclei with fine chromatin. Immunohistochemically, neuronal differentiation markers, including synaptophysin and neuronal nuclear antigen, were expressed in the tumor cells. Histopathological examination of the resected tissue confirmed a diagnosis of extraventricular neurocytoma. Magnetic resonance imaging was performed at 3 months post-surgery and demonstrated no evidence of tumor recurrence.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4888045PMC
http://dx.doi.org/10.3892/ol.2016.4487DOI Listing

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