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Culturing of Giardia lamblia under microaerobic conditions can impact metronidazole susceptibility by inducing increased expression of antioxidant enzymes.
Int J Parasitol Drugs Drug Resist
February 2025
Institute for Specific Prophylaxis and Tropical Medicine, Center for Pathophysiology, Infectiology, and Immunology, Medical University of Vienna, Kinderspitalgasse 15, A-1090, Vienna, Austria. Electronic address:
The microaerophilic/anaerobic protist Giardia lamblia is a world-wide occurring parasite of the human small intestine. It causes giardiasis which manifests as diarrhoea accompanied by other sequelae. Giardiasis is most commonly treated with either the 5-nitroimidazole metronidazole or the benzimidazole albendazole.
View Article and Find Full Text PDFStudy of clinical manifestations and etiologies of megaloblastic anemia in children.
Transfus Clin Biol
January 2025
Department of Pediatrics, Hedi Chaker University Hospital of Sfax, Tunisia; Faculty of Medecine, University of Sfax, Tunisia.
Background And Aim: Megaloblastic anemia (MA) is a rare pathology in childhood due, in the majority of cases, to a deficiency of folic acid and/or vitamin B12 (cobalamin). This study aims to determine the epidemiological, clinical, and paraclinical profiles of MA in children and to specify its etiologies, therapeutic modalities, and treatment responses.
Methods: This is a retrospective descriptive study of MA cases in children carried out in the General Pediatrics Department of the Hedi Chaker University Hospital of Sfax over a period of 42 years, from January 1979 to December 2021.
The effects of rain and drought on incidence of enteric disease in Pennsylvania (2010-2019).
Environ Res
February 2025
Department of Epidemiology and Biostatistics, Temple University Philadelphia, PA, USA; Water, Health and Applied Microbiology Lab, Department of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, ON, Canada. Electronic address:
Background: Campylobacter, nontyphoidal Salmonella, Cryptosporidium, and Giardia cause an estimated 1 million cases of domestically acquired waterborne diseases annually in the United States. Acute symptoms can include diarrhea and vomiting; however, these illnesses can result in longer term complications such as reactive arthritis, Guillan Barré syndrome and death, particularly in immunocompromised individuals. Precipitation and drought can plausibly increase the risk of enteric infections, but consensus in the literature is lacking.
View Article and Find Full Text PDF[A case of giardiasis diagnosed from a high output stoma after surgery for obstructive colorectal cancer].
Nihon Shokakibyo Gakkai Zasshi
July 2024
School of Health Sciences, College of Medical, Pharmaceutical and Health Sciences, Kanazawa University.
This report describes a case of giardiasis detected through stool smear analysis of postoperative stool fluid collected from a high output stoma for obstructive colorectal cancer. The patient, a 67-year-old male, underwent right hemicolectomy with ileostomy for obstructive colorectal cancer. The persistent excessive excretion of postoperative stool fluid from the stoma prompted a stool smear test.
View Article and Find Full Text PDFCoexistence of Helicobacter pylori and Giardia duodenalis causes severe iron deficiency anaemia in an adult male: a case report.
J Infect Dev Ctries
May 2024
Department of Medical Laboratory Sciences, Faculty of Applied Medical Sciences, The Hashemite University, Zarqa, Jordan.
Article Synopsis
- Iron deficiency anaemia (IDA) is the most common type of anaemia and is considered a major health issue worldwide, affecting people of all ages.
- This case study focuses on a 24-year-old male who experienced severe IDA due to co-infections with Helicobacter pylori and Giardia duodenalis, presenting symptoms like fatigue and abdominal pain for four weeks.
- After comprehensive tests confirmed severe IDA, the patient was treated with antibiotics and iron supplements, leading to significant improvement in both his symptoms and lab results.
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