RNA editing in cancer: Mechanistic, prognostic, and therapeutic implications.

Mol Cell Oncol

Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA; Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Published: March 2016

We have recently provided a comprehensive analysis of A-to-I RNA editing events in various cancer types, revealing many clinically relevant RNA editing sites and demonstrating that RNA editing can selectively affect cancer drug sensitivity. Our results unveil mechanistic, prognostic, and therapeutic implications for RNA editing in cancer.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905409PMC
http://dx.doi.org/10.1080/23723556.2015.1117702DOI Listing

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