TRPV1: Turning up the heat on intestinal tumorigenesis. | LitMetric

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TRPV1: Turning up the heat on intestinal tumorigenesis. | LitMetric

TRPV1: Turning up the heat on intestinal tumorigenesis.

Petrus R de Jong Samuel Bertin Eyal Raz

Mol Cell Oncol

Department of Medicine; UCSD ; La Jolla, CA USA.

Published: June 2016

TRP channels are associated with the development and progression of cancer but their precise molecular roles in these processes are unclear. Recently, we showed that the transient receptor potential cation channel, subfamily V, member 1 (TRPV1) ion channel is part of a negative feedback loop downstream of epidermal growth factor receptor signaling that suppresses intestinal tumorigenesis.

Download full-text PDF	Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905246	PMC
http://dx.doi.org/10.4161/23723556.2014.975619	DOI Listing

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