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TRPV1: Turning up the heat on intestinal tumorigenesis. | LitMetric

TRPV1: Turning up the heat on intestinal tumorigenesis.

Mol Cell Oncol

Department of Medicine; UCSD ; La Jolla, CA USA.

Published: June 2016

TRP channels are associated with the development and progression of cancer but their precise molecular roles in these processes are unclear. Recently, we showed that the transient receptor potential cation channel, subfamily V, member 1 (TRPV1) ion channel is part of a negative feedback loop downstream of epidermal growth factor receptor signaling that suppresses intestinal tumorigenesis.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905246PMC
http://dx.doi.org/10.4161/23723556.2014.975619DOI Listing

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