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Multichannel transceiver coil arrays are needed to enable parallel imaging and B1 manipulation in ultrahigh field MR imaging and spectroscopy. However, the design of such transceiver coils and coil arrays often faces technical challenges in achieving the required high operating frequency at the ultrahigh fields and sufficient electromagnetic (EM) decoupling between resonant elements. In this work, we propose a high impedance microstrip transmission line resonator (HIMTL) technique that has unique high frequency capability and adequate EM decoupling without the use of dedicated decoupling circuits.
View Article and Find Full Text PDFHigh-Frequency Ultrasound for Detecting Periodontal Inflammation: A Preclinical Diagnostic Accuracy Study.
J Periodontal Res
January 2025
Department of Radiology, University of Michigan, Ann Arbor, Michigan, USA.
Aim: Ultrasonography (US) has shown accuracy in imaging healthy periodontium. This study aims to evaluate the feasibility and accuracy of US for estimating dimensions of inflamed periodontium induced by ligature and bacteria.
Methods: Periodontal tissues of maxillary as well as mandibular premolars and molars in six female mini pigs were treated with ligature and three strains of bacteria for 4-10 weeks.
Dosimetric investigation of couch rotation angles in non-coplanar VMAT plans for lung cancer SBRT.
Front Oncol
December 2024
Department of Radiation Oncology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Background: This study aimed to investigate the effect of couch rotation angles on non-coplanar volumetric modulated arc therapy (ncVMAT) plan for stereotactic body radiotherapy (SBRT) in lung cancer patients and to evaluate the feasibility of clinically applying ncVMAT for SBRT.
Methods: Twenty-four lung cancer patients with a single lesion eligible for SBRT were enrolled in the study. Seven dual partial-arc VMAT plans with varying couch angles were designed for every patient.
High frequency CCR5 editing in human hematopoietic stem progenitor cells protects xenograft mice from HIV infection.
Nat Commun
January 2025
Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA.
The only cure of HIV has been achieved in a small number of people who received a hematopoietic stem cell transplant (HSCT) comprising allogeneic cells carrying a rare, naturally occurring, homozygous deletion in the CCR5 gene. The rarity of the mutation and the significant morbidity and mortality of such allogeneic transplants precludes widespread adoption of this HIV cure. Here, we show the application of CRISPR/Cas9 to achieve >90% CCR5 editing in human, mobilized hematopoietic stem progenitor cells (HSPC), resulting in a transplant that undergoes normal hematopoiesis, produces CCR5 null T cells, and renders xenograft mice refractory to HIV infection.
View Article and Find Full Text PDFDiscrete FIR filter-based Control.
ISA Trans
January 2025
Departamento de Ingeniería Eléctrica, CINVESTAV, CDMX, Mexico. Electronic address:
In control system design, managing measurement noise is a critical challenge, requiring a balance between responsiveness and noise suppression. Traditional methods often involve trade-offs, compromising either aspect. This paper proposes a novel solution by integrating a Finite Impulse Response (FIR) filter within the discrete controller transfer function, coupled with disturbance rejection through the Internal Model Principle (IMP).
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