The erythrocyte density test (EDT) and erythrocyte creatine concentration (ECE) as laboratory indexes of perinatal hypoxia.

To study the influence of gestational age and asphyxia on the behaviour of EDT and ECE a group of cuban control and asphyxiated newborns was investigated. A total number of 203 newborns at the age of 0-3 days of life, all with adequate weight for gestational age, were classified into 4 groups according to their gestational age, the 1 min and 5 min Apgar score and the presence of meconium stained amniotic fluid and/or respiratory distress syndrome immediately after birth. In the group of asphyxiated newborns higher values for both parameters were found when they were compared with the respective control groups (p less than 0.05). These techniques could help the neonatologists to more precisely identify newborns with severe perinatal asphyxia and to improve the prognosis of the outcome.