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Clinical relevance and prognostic impact of the classification between multibacillary and paucibacillary forms of cutaneous tuberculosis: A 24-year retrospective multicenter study.

Ann Dermatol Venereol

December 2024

Infectious and Tropical Diseases Department, Hôpitaux Universitaires Pitié Salpêtrière-Charles Foix, AP-HP, Paris, France; Sorbonne University, INSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique, Paris, France.

Objectives: Cutaneous tuberculosis (CTB) may be over-diagnosed due to imprecise diagnostic criteria or overlooked where mycobacterial investigations are negative. We evaluated the distinction between multibacillary and paucibacillary forms of CTB, as well as drug resistance and cure rates according to the results of mycobacterial investigations.

Methods: We included retrospectively all patients diagnosed with CTB from 1995 to 2018 in two hospitals in Paris.

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Article Synopsis
  • Tuberculides are immune reactions to tuberculosis that occur in healthy individuals, and this study focuses on their characteristics and treatment responses in a North Indian healthcare center.
  • Analyzing clinical records from 2000 to 2019, the study identified 34 patients with tuberculides, with lichen scrofulosorum being the most prevalent type, followed by other forms like erythema nodosum.
  • The findings highlight that tuberculides can indicate hidden tuberculosis infections, aiding in early diagnosis and effective treatment with a standard six-month anti-tubercular therapy regimen.
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Papulonecrotic tuberculid.

CMAJ

February 2024

Department of Dermatovenereology (Zhang, Chen), Chengdu Second People's Hospital, Chengdu, Sichuan, China; Sexually Transmitted Disease Institute (Wu), Shanghai Skin Disease Hospital, School of Medicine, Tongji University, Shanghai, China

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