Why NAD(+) Declines during Aging: It's Destroyed.

Cell Metab

Paul F. Glenn Center for the Biological Mechanisms of Aging, Department of Genetics, Harvard Medical School, Boston, MA 02115, USA; Department of Pharmacology, University of New South Wales, Sydney 2052, Australia. Electronic address:

Published: June 2016

NAD(+) is required not only for life but for a long life. In this issue, Camacho-Pereira et al. (2016) implicate CD38 in the decline of NAD(+) during aging, with implications for combating age-related diseases.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5088772PMC
http://dx.doi.org/10.1016/j.cmet.2016.05.022DOI Listing

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