Active optics has attracted considerable interest from researchers in synchrotron radiation facilities because of its capacity for x-ray wavefront correction. Here, we report a novel and efficient technique for correcting or modulating a mirror surface profile based on laser-heating-induced thermal expansion. An experimental study of the characteristics of the surface thermal deformation response indicates that the power of a milliwatt laser yields a bump height as low as the subnanometer scale and that the variation of the spot size modulates the response function width effectively. In addition, the capacity of the laser-heating technique for free-form surface modulation is demonstrated via a one-dimensional surface correction experiment. The developed method is a promising new approach toward effective x-ray active optics coupled with at-wavelength metrology techniques.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1364/OL.41.002815 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
The Impact of Optical Undersampling on the Ca Signal Resolution in Ca Imaging of Spontaneous Neuronal Activity.
J Integr Neurosci
January 2025
Neuroscience Department, University of Connecticut Health, School of Medicine, Institute for Systems Genomics, Farmington, CT 06030, USA.
Background: In neuroscience, Ca imaging is a prevalent technique used to infer neuronal electrical activity, often relying on optical signals recorded at low sampling rates (3 to 30 Hz) across multiple neurons simultaneously. This study investigated whether increasing the sampling rate preserves critical information that may be missed at slower acquisition speeds.
Methods: Primary neuronal cultures were prepared from the cortex of newborn pups.
Exploring the Pathophysiology, Diagnosis, and Treatment Options of Multiple Sclerosis.
J Integr Neurosci
January 2025
Department of Ophthalmology, University Hospital of Udine, 33100 Udine, Italy.
The complicated neurological syndrome known as multiple sclerosis (MS) is typified by demyelination, inflammation, and neurodegeneration in the central nervous system (CNS). Managing this crippling illness requires an understanding of the complex interactions between neurophysiological systems, diagnostic techniques, and therapeutic methods. A complex series of processes, including immunological dysregulation, inflammation, and neurodegeneration, are involved in the pathogenesis of MS.
View Article and Find Full Text PDFScalable Manufacturing Method for Model Protein-Loaded PLGA Nanoparticles: Biocompatibility, Trafficking and Release Properties.
Pharmaceutics
January 2025
MyBiotech GmbH, Industriestraße 1B, 66802 Überherrn, Germany.
: Drug delivery systems (DDSs) offer efficient treatment solutions to challenging diseases such as central nervous system (CNS) diseases by bypassing biological barriers such as the blood-brain barrier (BBB). Among DDSs, polymeric nanoparticles (NPs), particularly poly(lactic-co-glycolic acid) (PLGA) NPs, hold an outstanding position due to their biocompatible and biodegradable qualities. Despite their potential, the translation of PLGA NPs from laboratory-scale production to clinical applications remains a significant challenge.
View Article and Find Full Text PDFNeuroprotective Actions of Cannabinoids in the Bovine Isolated Retina: Role of Hydrogen Sulfide.
Pharmaceuticals (Basel)
January 2025
Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, Texas Southern University, Houston, TX 77004, USA.
Both hydrogen sulfide and endocannabinoids can protect the neural retina from toxic insults under in vitro and in vivo conditions. The aim of the present study was two-fold: (a) to examine the neuroprotective action of cannabinoids [methanandamide and 2-arachidonyl glycerol (2-AG)] against hydrogen peroxide (HO)-induced oxidative damage in the isolated bovine retina and (b) to evaluate the role of endogenously biosynthesized hydrogen sulfide (HS) in the inhibitory actions of cannabinoids on the oxidative stress in the bovine retina. Isolated neural retinas from cows were exposed to oxidative damage using HO (100 µM) for 10 min.
View Article and Find Full Text PDFGround-Target Recognition Method Based on Transfer Learning.
Sensors (Basel)
January 2025
College of Communication Engineering, Jilin University, Changchun 130012, China.
A moving ground-target recognition system can monitor suspicious activities of pedestrians and vehicles in key areas. Currently, most target recognition systems are based on devices such as fiber optics, radar, and vibration sensors. A system based on vibration sensors has the advantages of small size, low power consumption, strong concealment, easy installation, and low power consumption.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!