Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910892PMC
http://dx.doi.org/10.1164/rccm.201511-2129LEDOI Listing

Publication Analysis

Top Keywords

extracellular mrna
4
mrna detected
4
detected tethered
4
tethered lipoplex
4
lipoplex nanoparticle
4
nanoparticle biochip
4
biochip lung
4
lung adenocarcinoma
4
adenocarcinoma detection
4
extracellular
1

Similar Publications

Impact of H37Rv Infection on Extracellular Vesicle Cargo in Macrophages: Implications for Host-Pathogen Interaction.

Microorganisms

November 2024

Department of Microbiology, Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas, Mexico City 14080, Mexico.

Tuberculosis (TB) is one of the most common respiratory infections worldwide, and it is caused by (). employs immune evasion mechanisms that allow the disease to become chronic. Despite extensive research, the host-pathogen interaction remains incompletely understood.

View Article and Find Full Text PDF

: Pyroptosis, an inflammatory cell death, is involved in the progression of atherosclerosis. Pyroptosis in endothelial cells (ECs) and its underlying mechanisms in atherosclerosis are poorly understood. Here, we investigated the role of a caspase-4/5-NF-κB pathway in pyroptosis in palmitic acid (PA)-stimulated ECs and EVs as players in pyroptosis.

View Article and Find Full Text PDF

mRNA-based vaccines against the COVID-19 pandemic have propelled the use of nucleic acids for drug delivery. Conventional lipid-based carriers, such as liposomes and nanolipogels, effectively encapsulate and deliver RNA but are hindered by issues such as premature burst release and immunogenicity. To address these challenges, cell membrane-coated nanoparticles offer a promising alternative.

View Article and Find Full Text PDF

Inflammatory Stimulation Upregulates the Receptor Transporter Protein 4 (RTP4) in SIM-A9 Microglial Cells.

Int J Mol Sci

December 2024

Department of Pharmacology and Therapeutic Innovation, School of Pharmaceutical Sciences, Nagasaki University, Nagasaki 852-8521, Japan.

The receptor transporter protein 4 (RTP4) is a receptor chaperone protein that targets class A G-protein coupled receptor (GPCR)s. Recently, it has been found to play a role in peripheral inflammatory regulation, as one of the interferon-stimulated genes (ISGs). However, the detailed role of RTP4 in response to inflammatory stress in the central nervous system has not yet been fully understood.

View Article and Find Full Text PDF

Slit1 Promotes Hypertrophic Scar Formation Through the TGF-β Signaling Pathway.

Medicina (Kaunas)

December 2024

Department of Rehabilitation Medicine, Hangang Sacred Heart Hospital, College of Medicine, Hallym University, 94-200 Yeongdeungpo-Dong, Yeongdeungpo-Ku, Seoul 07247, Republic of Korea.

Slit1 is a secreted protein that is closely related to cell movement and adhesion. Few studies related to fibrosis exist, and the preponderance of current research is confined to the proliferation and differentiation of neural systems. Hypertrophic scars (HTSs) are delineated by an overproduction of the extracellular matrix (ECM) by activated fibroblasts, leading to anomalous fibrosis, which is a severe sequela of burns.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!