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Observer-rated environmental sensitivity and its characterization at behavioral, genetic, and physiological levels.
Dev Psychopathol
January 2025
School of Psychology, University of Surrey, Surrey, UK.
This study investigated the psychometric properties of the Highly Sensitive Child-Rating System (HSC-RS), the existence of sensitivity groups, and the characterization of sensitivity at behavioral, genetic, and physiological levels in 541 preschoolers (() = 3.56(0.27); 45%male; 87%Caucasian).
View Article and Find Full Text PDFLacosamide as an Adjunctive Therapy in Drug-Resistant Absence Epilepsy: Successful Treatment of Four Patients.
Iran J Child Neurol
September 2024
Department of Clinical Pathology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.
Absence epilepsy is one of the most common epileptic syndromes in children, and despite its benign nature, a percentage of these children are drug-resistant. This study presents four cases of drug-resistant absence epilepsy in children who were unresponsive to traditional antiepileptic drugs. The study reports the successful use of Lacosamide as an adjunctive therapy to completely control symptoms and electroencephalogram (EEG) abnormalities.
View Article and Find Full Text PDFAcute symptomatic seizures in patients with recurrent ischemic stroke: A multicentric study.
Epileptic Disord
December 2024
Serviço de Neurologia, Departamento de Neurociências e Saúde Mental, Hospital de Santa Maria, ULS Santa Maria, Lisbon, Portugal.
Article Synopsis
- The study investigated the risk of acute symptomatic seizures in patients who experience recurrent strokes compared to those having their first stroke, looking at data from stroke patients over a 5-year period.
- The findings revealed that the risk of seizures was similar for both groups, with 5.1% for recurrent stroke patients and 4.5% for first-time patients, suggesting prior stroke history doesn’t increase seizure risk.
- Other factors like age, sex, and hemorrhagic changes were linked to seizures only in first-time stroke patients, indicating different risk profiles between the two groups; further research in larger studies is encouraged to validate these results.
Isolated Psychiatric Symptoms in Children With Anti-N-Methyl-d Aspartate Receptor Encephalitis.
Pediatr Neurol
October 2024
Department of Pediatrics, University of Texas at Austin and Dell Medical School, Austin, Texas.
Background: Isolated psychiatric symptoms can be the initial symptom of pediatric anti-N-methyl-d-aspartate (NMDA) receptor autoimmune encephalitis (pNMDARE). Here we report on the prevalence of isolated psychiatric symptoms in pNMDARE. We also assess whether initial neurodiagnostic tests (brain magnetic resonance imaging [MRI], electroencephalography [EEG], and/or cerebrospinal fluid [CSF] white blood cell count) are abnormal in children with isolated psychiatric symptoms and pNMDARE.
View Article and Find Full Text PDFAltered fronto-limbic-motor response to stress differs between functional and epileptic seizures in a TBI model.
Epilepsy Behav
August 2024
Department of Neurology, University of Alabama at Birmingham (UAB), Birmingham, AL, USA; UAB Epilepsy Center, University of Alabama at Birmingham (UAB), Birmingham, AL, USA; Department of Neurobiology, University of Alabama at Birmingham (UAB), Birmingham, AL, USA; Department of Neurosurgery, University of Alabama at Birmingham (UAB), Birmingham, AL, USA. Electronic address:
Background And Objectives: Psychogenic nonepileptic (functional) seizures (FS) clinically resemble epileptic seizures (ES) with both often preceded by traumatic brain injury (TBI). FS and ES emergence and occurrence after TBI may be linked to aberrant neurobehavioral stress responses. We hypothesized that neural activity signatures in response to a psychosocial stress task would differ between TBI + FS and TBI + ES after controlling for TBI status (TBI-only).
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