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http://dx.doi.org/10.1002/mus.25219 | DOI Listing |
Muscle Nerve
October 2024
Division of Neurology, Institute of Clinical Neurophysiology, University Medical Center Ljubljana, Ljubljana, Slovenia.
Introduction/aims: Diagnostic criteria for multifocal motor neuropathy (MMN) and multifocal acquired demyelinating sensorimotor neuropathy (MADSAM) require the involvement of at least two peripheral nerves. However, many patients with very similar features have clinical involvement of only a single peripheral nerve, which may preclude their correct diagnosis and treatment. The present study aimed to present a cohort of such patients and discuss the role of ultrasonography (US) in their diagnosis.
View Article and Find Full Text PDFRev Med Suisse
July 2023
Service de neurologie, Centre hospitalier du Valais romand, Hôpital du Valais, Hôpital de Sion, 1951 Sion.
Peripheral facial palsy is a common, often idiopathic and self-limiting mononeuropathy. However, secondary facial palsies require specific management: they are most often of infectious, vascular or dysimmune causes. The presence of red flags in the history, clinical examination or medical follow-up should alert clinicians.
View Article and Find Full Text PDFFront Neurol
September 2021
Department of Neurology, College of Medicine, St. Vincent's Hospital, The Catholic University of Korea, Seoul, South Korea.
Neuralgic amyotrophy (NA) is an acute, monophasic, painful inflammatory dysimmune focal, or multifocal mononeuropathy. The lesion in NA is not always restricted to the brachial plexus but also involves individual nerves or branches. The prognosis of NA is less favorable than previously assumed, but the reasons for poor recovery remain unknown.
View Article and Find Full Text PDFJ Neurol
February 2022
Department of Neuroscience, Reproductive Sciences and Odontostomatology, University of Naples "Federico II", Via Pansini, 5, 81025, Naples, Italy.
Compression of the median nerve at the carpal tunnel can give demyelinating features and result in distal motor latency (DML) prolongation fulfilling the EFNS/PNS demyelinating criteria for chronic inflammatory demyelinating polyneuropathy (CIDP). Accordingly, being carpal tunnel syndrome (CTS) common in the general population, the EFNS/PNS guidelines recommend excluding the DML of the median nerve when DML prolongation may be consistent with median neuropathy at the wrist from CTS. The main aims of this study were to verify whether the inclusion of DML of the median nerve (when consistent with CTS) could improve electrophysiological diagnostic accuracy for CIDP and if the median nerve at the carpal tunnel was more prone to demyelination.
View Article and Find Full Text PDFJ Neuroimmunol
December 2020
Neurology Unit, "A. Manzoni" Hospital - ASST Lecco, Lecco, Italy.
Multifocal motor neuropathy is a purely motor neuropathy with a probably dysimmune pathogenesis, supported by the presence of anti-GM1 IgM antibodies in about half of the cases. Single nerve involvement allows for diagnosis of possible multifocal motor neuropathy. We present the case of a middle age man presenting with progressive weakness and hypotrophy in the left leg and difficulty in walking, in which we have diagnosed a dysimmune mononeuropathy.
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