The aim of the study was to examine changes in the microbiota gastric an diseases gastroduodenal zone to highlight gender features. We examined patients at esophagogastroduodenoscopy performed biopsies mucous membrane fence with the wall mucus, followed by microscopic, microbiological, histological examination. When polyposis and gastric cancer incidence in women H. pylori was less than that of men. In diseases of the gastroduodenal zone level changes gastric microbiota reflects the morphological condition of the mucous membrane, the gender differences in most cases are not detected. The highest frequency of inoculation and the amount typical for Streptococcus, Staphylococcus epidermidis, H. pylori, Candida spp., Escherichia coli, Lactobacilli. Status microbiota gastroduodenal zone in patients with consider when correcting their treatment.

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