Unlabelled: We earlier reported the clinical effects of TJ-48 on side-effects of anti-tumor agents. In this report an immunological examination was conducted on administration of TJ-48 for postoperative gastric cancer.

Materials And Methods: Blast formation of mouse lymphocyte to which patient serum was added. TNF activity, LAK activity and 2-5AS activity before and after administration of TJ-48 were measured in 19 cases of gastric cancer.

Results: Blast formation of mouse lymphocytes after administration showed a tendency to increase more than before. TNF activities tended to decrease more after administration than before. 2-5AS activities indicated a tendency to decrease more after administration than before. Little difference was manifest between LAK activities before and after administration.

Conclusion: The action of non-specific immunosuppressive factor was suggested to be lowered after administration of TJ-48 for postoperative gastric cancer.

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