Unlabelled: We earlier reported the clinical effects of TJ-48 on side-effects of anti-tumor agents. In this report an immunological examination was conducted on administration of TJ-48 for postoperative gastric cancer.
Materials And Methods: Blast formation of mouse lymphocyte to which patient serum was added. TNF activity, LAK activity and 2-5AS activity before and after administration of TJ-48 were measured in 19 cases of gastric cancer.
Results: Blast formation of mouse lymphocytes after administration showed a tendency to increase more than before. TNF activities tended to decrease more after administration than before. 2-5AS activities indicated a tendency to decrease more after administration than before. Little difference was manifest between LAK activities before and after administration.
Conclusion: The action of non-specific immunosuppressive factor was suggested to be lowered after administration of TJ-48 for postoperative gastric cancer.
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Pharmaceuticals (Basel)
September 2024
Department of Cardiology and Neurology, Kyung Hee University College of Korean Medicine, Kyung Hee University Medical Center, Seoul 02447, Republic of Korea.
Background/objectives: Anemia is a global health issue affecting diverse populations, particularly older adults, and conventional treatments often show limited efficacy. This study aimed to evaluate the utilization and effectiveness of Sipjeondaebotang (SDT), a prescription drug used in traditional East Asian medicine, in treating various types of anemia.
Methods: A scoping review was conducted following Arksey and O'Malley's framework and PRISMA-ScR guidelines.
Neuropeptides
August 2021
Department of Surgery Center, Fuchu Hospital, Osaka, Japan.
FOLFOXIRI (fluorouracil, leucovorin, oxaliplatin, and irinotecan) plus bevacizumab is the preferred first-line treatment for right-sided metastatic colorectal cancer with RAS mutation. However, severe adverse events are common in Japanese patients. We report the successful management of multiple stage IV colorectal cancers in a patient who received multidisciplinary treatment, including chemotherapy and Japanese Kampo medicine.
View Article and Find Full Text PDFMol Clin Oncol
September 2020
Department of Thoracic Surgery, Akita Red Cross Hospital, Akita 010-1495, Japan.
Kampo medicines have been used to reduce chemotherapy-induced adverse events. However, whether Kampo medicine can improve the prognosis of cancer remains unclear. The present study aimed to clarify the effect of Juzentaihoto (TJ-48) on patients with postoperative recurrence of non-small cell lung cancer.
View Article and Find Full Text PDFEvid Based Complement Alternat Med
April 2018
Department of Clinical Epidemiology and Health Economics, The University of Tokyo, Tokyo, Japan.
Background: Infectious complications after hip fracture surgery are common in the elderly. Although experimental studies have suggested that kampo medicine, Hochu-ekki-to and Juzen-taiho-to, can prevent infectious complications, only a few small clinical studies have been published to date.
Primary Study Objective: The aim of the present study is to investigate the impact of Hochu-ekki-to or Juzen-taiho-to on postoperative infectious complications in patients undergoing surgery for hip fracture.
Gan To Kagaku Ryoho
December 2015
Dept. of Surgery, Japanese Red Cross Kanazawa Hospital.
Operative stress causes various changes in the body, and immunological hypofunction and malnutrition increase complications and adversely affect long-term prognosis. Therefore, reducing operative stress as much as possible, minimizing complications after surgery, and aiming for a satisfactory postoperative course are important. However, difficult and unresolvable situations often arise when only the conventional Western medicine approach is used because the situation and condition varies for each patient.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!