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Involvement of the small intestine in systemic mast cell disease. | LitMetric

AI Article Synopsis

  • - A patient was found to have mast cell infiltration in the small intestine without the usual skin symptoms associated with mast cell disease.
  • - She exhibited subtotal villous atrophy, which improved when she switched to a gluten-free diet.
  • - The authors suggest new diagnostic criteria for mast cell disease in the small intestine and explore its connection to coeliac disease through a literature review.

Article Abstract

A patient is reported with mast cell infiltration of the small intestine in the absence of the skin involvement characteristic of mast cell disease. She also had subtotal villous atrophy responsive to a gluten-free diet. Criteria for diagnosing mast cell disease of the small intestine are proposed. The literature of small intestinal mast cell disease is reviewed and the relationship to coeliac disease is discussed.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1413129PMC
http://dx.doi.org/10.1136/gut.16.11.918DOI Listing

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