This case study reports on a rare case of a woman with Behcet's disease (BD), uterine malformation and antiphospholipid syndrome, who successfully delivered a baby without any complications during the perinatal period. The woman, who was diagnosed with BD with relapsing oral, ocular, and genital involvement 8 years ago, registered in our clinic with a history of two inevitable miscarriages. Laboratory findings were positive for anti-β -glycoprotein I antibodies (anti-β -GP-I). Three-dimensional ultrasound showed that her uterus was unicornuate, with only a normal left side. After treatment, the woman had a cesarean section for breech presentation of a healthy male infant weighing 2700 g. The postpartum period was uneventful. The possible effects of BD on pregnancy outcomes and how to manage BD patients are discussed with a review of the literature.
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http://dx.doi.org/10.1111/aji.12530 | DOI Listing |
Rheumatology (Oxford)
March 2025
Division of Nephrology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Rheumatology (Oxford)
March 2025
Rheumatic and Immunologic Diseases, Cleveland Clinic, Cleveland, OH, USA.
Systemic vasculitis can present with different manifestations, some of which require unique approaches. This session at the 21st International Vasculitis Workshop, examined six studies focused on "Management of Special Situations". In ANCA-associated vasculitis (AAV), two institutions reported on their experience with subglottic stenosis (SGS) from the standpoint of histologic features and management compared to patients with idiopathic SGS.
View Article and Find Full Text PDFMod Rheumatol
March 2025
Department of Rheumatology and Allergology, St. Marianna University School of Medicine, Kawasaki, Japan.
Objectives: Enthesitis has been reported in Behçet's disease (BD); however, the analysis remains insufficient. This study examined the clinical characteristics of patients with BD presenting with enthesitis.
Methods: A single-centre, observational, retrospective cohort study was conducted by reviewing medical records.
CJC Open
February 2025
Department of Cardiac Surgery, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.
Background: Aortic regurgitation (AR) is a condition associated with significant morbidity and mortality, particularly in severe cases. The J-Valve system, next-generation transcatheter heart valve, may overcome the procedural challenges associated with treating pure AR. This study reported the outcome of use of the J-Valve for treatment of AR.
View Article and Find Full Text PDFMedComm (2020)
March 2025
Neutrophil extracellular traps (NETs) are unique fibrous structures released by neutrophils in response to various pathogens, exhibiting both anti-inflammatory and proinflammatory effects. In autoimmune conditions, NETs serve as crucial self-antigens triggering inflammatory cascades by activating the inflammasome and complement systems, disrupting self-tolerance mechanisms and accelerating autoimmune responses. Furthermore, NETs play a pivotal role in modulating immune cell activation, affecting adaptive immune responses.
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