The selection of articles in this special issue was solicited following the highly successful , held in Taormina (Italy) in October 2014, and organised under the chairmanship of Professor Ferdinando Nicoletti. All papers were written and submitted after the conclusion of the meeting and were independently peer-reviewed. As always, we are grateful to those experts who have given their time to review the papers. The original studies and reviews cover topics within the mGlu receptor field ranging from basic molecular and physiological studies (papers by Farrow; Dalton Hogg Kalinowska & Francesconi; Kahl & Fendt) to studies that are focussed on specific functions and/or diseases where mGlu receptors are implicated or may be therapeutic targets. This covers areas such as Schizophrenia (Woźniak Klar Maj ) Stress Disorders (Peterlik ) Parkinson’s Disease (Klar Morin ) Epilepsy (Qian & Tang), Pain (Koga Palazzo ) and this reflects the wide range of mechanisms and diseases that show involvement of these receptors.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4983751 | PMC |
http://dx.doi.org/10.2174/1570159x1405160601201555 | DOI Listing |
iScience
January 2025
Department of Mechanical Engineering, Pohang University of Science and Technology (POSTECH), Pohang, South Korea.
The heart, with its complex structural and functional characteristics, plays a critical role in sustaining life by pumping blood throughout the entire body to supply nutrients and oxygen. Engineered heart tissues have been introduced to reproduce heart functions to understand the pathophysiological properties of the heart and to test and develop potential therapeutics. Although numerous studies have been conducted in various fields to increase the functionality of heart tissue to be similar to reality, there are still many difficulties in reproducing the blood-pumping function of the heart.
View Article and Find Full Text PDFFront Psychol
January 2025
Department of Psychosomatic Medicine and Psychotherapy, LWL-University Hospital, Ruhr-Universität Bochum, Bochum, Germany.
Introduction: Intrusive memories occur frequently after potentially traumatic events and form a core symptom of posttraumatic stress disorder (PTSD) if they persist. The translational approach of visuospatial interventions tries to target those intrusive memories in order to reduce their frequency predominantly using an intervention including as one component the computer game Despite promising results, the application of has critical drawbacks, e.g.
View Article and Find Full Text PDFInt J Chron Obstruct Pulmon Dis
January 2025
School of Translational Medicine, Monash University, Melbourne, VIC, Australia.
Purpose: Oral corticosteroids (OCS) are recommended for the treatment of exacerbations in people with COPD; however, high cumulative lifetime doses (≥1000mg prednisolone-equivalent) are associated with adverse health effects. This issue is well defined in asthma but is less well understood in COPD. The aim of this study was to examine cumulative OCS dispensed to people with COPD over 12 months.
View Article and Find Full Text PDFBrain Behav Immun Health
February 2025
University Center for Research and Development, Chandigarh University, Mohali, Punjab, India.
Background And Objective: Lyme disease, caused by , presents major health challenges worldwide, leading to serious neurological and musculoskeletal issues that impact patients' lives and healthcare systems. This systematic review and meta-analysis aim to determine the prevalence and link between Lyme disease and these complications, aiming to enhance clinical and public health approaches.
Methods: We systematically searched PubMed, EMBASE, and Web of Science up until April 01, 2024, to find studies reporting the prevalence and severity of neurological and musculoskeletal complications associated with Lyme disease.
Brain Behav Immun Health
February 2025
School of Nursing, University of Pennsylvania, Philadelphia, PA, 19104, USA.
The assessment of salivary cortisol in community settings has gained popularity in biobehavioral research due to its noninvasive sampling, ease of handling and storage, and suitability for repeated sampling in short intervals. Ensuring consistent methodological practices for salivary cortisol is essential. This systematic review critically examines salivary cortisol collection procedures, data cleaning, and analysis to better understand its role in biobehavioral research within community populations.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!