Objective: The aim of the present study was to evaluate the effect of stimulation rate on speech perception and sound quality for the fine structure strategy FS4 and the envelope-based strategy high definition continuous interleaved sampling (HDCIS).
Study Design: Randomized crossover trial with four conditions.
Setting: Tertiary referral.
Patients: Twenty-six postlingually deafened adult cochlear implant (CI) recipients were included.
Intervention: All subjects were equipped with four coding strategies: FS4 with high rate on the envelope channels (on average 1376 pps/ch), FS4 low rate (750 pps/ch), and HDCIS with the same high and low rates. A "flat-charge map" was used for all four strategies. Only the loudness was balanced between programs. All tests were performed acutely in a double blind manner and a randomized sequence.
Main Outcome Measures: Monosyllables in quiet and subjective sound quality.
Results: Mean monosyllables scores at 65 dB in quiet were 25.5% correct with HDCIS low rate, 27.2% correct with HDCIS high rate, 25.2% with FS4 low rate, and 33.1% with FS4 high rate. Performance with high stimulation rates was significantly higher than with the low rate settings. Subjective sound quality measured with visual analogue scales showed that for naturalness of speech, the improvement with a high rate version was only evident with the FS4 strategy. In both FS4 and HDCIS, higher stimulation rates elicited a higher pitch and were perceived as less dull than lower rates.
Conclusion: A high rate of stimulation resulted in better speech recognition in both strategies and a favorable subjective sound quality for FS4 in all tested settings.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1097/MAO.0000000000001107 | DOI Listing |
Discov Oncol
January 2025
Department of General Surgery, The Second Affiliated Hospital of the Air Force Medical University, Xi'an, 710038, China.
A common digestive system cancer with a dismal prognosis and a high death rate globally is breast cancer (BRCA). BRCA recurrence, metastasis, and medication resistance are all significantly impacted by cancer stem cells (CSCs). However, the relationship between CSCs and the tumor microenvironment in BRCA individuals remains unknown, and this information is critically needed.
View Article and Find Full Text PDFOncol Ther
January 2025
Coordinator of the International Head and Neck Scientific Group, Padua, Italy.
Introduction: Laryngeal chondrosarcoma (CS) is a rare indolent malignant tumor. High-grade (G3), dedifferentiated (DD), and myxoid (MY) CSs are considered more aggressive subtypes due to their metastatic potential and relatively poor outcomes. The aim of this systematic review is to evaluate treatment modalities and survival outcomes in patients affected by these rarer CS subtypes.
View Article and Find Full Text PDFBackground: The armamentarium of medical therapies to treat inflammatory bowel disease (IBD) continues to grow, which has expanded treatment options, particularly after first biologic failure. Currently, there are limited studies investigating the predictive value of first biologic primary non-response (PNR) on subsequent biologic success. Our objective was to determine if PNR to the first biologic for IBD is predictive of response to subsequent biologic therapy.
View Article and Find Full Text PDFSci Rep
January 2025
College of Chemistry and Chemical Engineering, Tarim University, Alar, 843300, Xinjiang, China.
We have developed a novel S-scheme mechanism to expand the photoresponse range of BiSiO. This study reports the successful creation of a CN/BS heterojunction photocatalyst, which is composed of g-CN and BiSiO. The synthesis was achieved through a simple two-step procedure, involving hydrothermal treatment and subsequent calcination.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Mechanical Engineering, College of Engineering and Computer Sciences, Jazan University, P.O Box 45124, Jazan, Saudi Arabia.
Fluid flow across a Riga Plate is a specialized phenomenon studied in boundary layer flow and magnetohydrodynamic (MHD) applications. The Riga Plate is a magnetized surface used to manipulate boundary layer characteristics and control fluid flow properties. Understanding the behavior of fluid flow over a Riga Plate is critical in many applications, including aerodynamics, industrial, and heat transfer operations.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!