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Current Development of Mesenchymal Stem Cell-Derived Extracellular Vesicles.

Cell Transplant

January 2025

Cells Good (Xiamen) Inc. Huli, Xiamen Torch Development Zone, Fujian, China.

Mesenchymal stem cells (MSCs) are pluripotent stem cells with self-renewal. They play a critical role in cell therapy due to their powerful immunomodulatory and regenerative effects. Recent studies suggest that one of the key therapeutic mechanisms of MSCs seems to derive from their paracrine product, called extracellular vesicles (EVs).

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A review of the roles of exosomes in salivary gland diseases with an emphasis on primary Sjögren's syndrome.

J Dent Sci

January 2025

State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China.

Salivary gland diseases encompass a broad range of conditions, including autoimmune, inflammatory, obstructive, and neoplastic disorders, significantly impacting oral health and overall well-being. Recent research has highlighted the crucial role of exosomes, small extracellular vesicles, in these diseases. Exosomes mediate intercellular communication by transferring bioactive molecules such as proteins, microRNAs, and lipids, positioning them as potential diagnostic biomarkers and therapeutic agents.

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A scientometric study on research trends and characteristics of discoid lupus erythematosus.

J Dent Sci

January 2025

Department of Oral and Maxillofacial-Head and Neck Oncology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Background/purpose: Discoid lupus erythematosus (DLE) serves as an interdisciplinary disease involved in dermatology and stomatology in many cases. The purpose of this study was to analyze the scientometric characteristics and research trends of DLE.

Materials And Methods: All the papers on DLE were comprehensively retrieved from the Scopus database.

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Cardiovascular diseases cause significant morbidity and mortality worldwide. Engineered cardiac organoids are being developed and used to replicate cardiac tissues supporting cardiac morphogenesis and development. These organoids have applications in drug screening, cardiac disease models and regenerative medicine.

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Transcranial direct current stimulation (tDCS) has gained significant attention as a potential therapeutic tool in stroke rehabilitation, promoting neuroplasticity and enhancing motor and cognitive recovery. Despite growing research, the field's evolution and key trends remain underexplored. This study aims to perform a bibliographic analysis of publications related to tDCS and stroke rehabilitation to assess the growth of the field.

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