Inositol polyphosphate binding specificity of the jasmonate receptor is largely determined by the F-box protein COI1.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972291 | PMC |
http://dx.doi.org/10.1104/pp.16.00694 | DOI Listing |
Biochemistry
December 2024
Gavin Herbert Eye Institute - Center for Translational Vision Research, Department of Ophthalmology, University of California, Irvine, Irvine, California 92697, United States.
Arrestins halt signal transduction by binding to the phosphorylated C-termini of activated G protein-coupled receptors. Arrestin-1, the first subtype discovered, binds to rhodopsin in rod cells. Mutations in , the gene encoding Arrestin-1, are linked to Oguchi disease, characterized by delayed dark adaptation.
View Article and Find Full Text PDFMicroPubl Biol
November 2024
Laboratory for Molecular Cell Biology, London WC1E 6BT, UK, University College London, London, England, United Kingdom.
J Biol Chem
December 2024
Faculty of Science and Engineering, Department of Biology, Konan University, Kobe, Japan; Institute of Integrative Neurobiology, Konan University, Kobe, Japan. Electronic address:
Phosphate (Pi) homeostasis at the cellular level is crucial, requiring coordinated Pi uptake, storage, and export. However, the regulatory mechanisms, particularly those governing Pi export, remain elusive, despite their relevance to human diseases like primary familial brain calcification. While Xpr1, conserved across eukaryotes, is the only known Pi exporter, the existence of additional Pi exporting factors is evident; however, these factors have been poorly characterized.
View Article and Find Full Text PDFImmunity
December 2024
Department of Biomedical Sciences, University of Lausanne, Lausanne, Switzerland. Electronic address:
The gene inositol polyphosphate-5-phosphatase D (INPP5D), which encodes the lipid phosphatase SH2-containing inositol polyphosphate 5-phosphatase 1 (SHIP1), is associated with the risk of Alzheimer's disease (AD). How it influences microglial function and brain physiology is unclear. Here, we showed that SHIP1 was enriched in early stages of healthy brain development.
View Article and Find Full Text PDFActa Crystallogr B Struct Sci Cryst Eng Mater
December 2024
CRM2, UMR CNRS 7036, Université de Lorraine, 54500 Nancy, France.
Quercetin, a bioflavonoid abundant in plants, boasts antioxidant properties and plays a crucial role in various biological systems. The diffraction data of a quercetin dihydrate crystal have been measured at 20 (2) K to ultrahigh resolution (0.30 Å) using a synchrotron X-ray source.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!