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Programmable DNA Hydrogels with Zinc Oxide Nanoparticles and Cisplatin for Diagnosis and Treatment of Oral Squamous Cell Carcinoma.
Adv Healthc Mater
December 2024
School of Materials and Engineering, Ho hai university, Nanjing, 210000, China.
This study explores the potential of DNA hydrogels as a novel approach for diagnosing and treating Oral Squamous Cell Carcinoma (OSCC). In the experiment, DNA hydrogels are synthesized and loaded with Zinc Oxide Nanoparticles (ZnO NPs) and Cisplatin. In vitro experiments evaluated drug delivery efficacy and the effect on cancer cell viability.
View Article and Find Full Text PDFUnderstanding the National Healthcare Ecosystem to Position Medical Affairs as a Strategic Element: Lessons Learned from AstraZeneca Spain.
Pharmaceut Med
December 2024
Medical Affairs Department, AstraZeneca Farmacéutica Spain, C. del Puerto de Somport 21-23, Fuencarral-El Pardo, 28050, Madrid, Spain.
Introduction: The rapidly evolving healthcare landscape has prompted Medical Affairs (MA) departments within pharmaceutical companies to transition from their traditional role as information providers to becoming strategic partners in the healthcare ecosystem. Responding to the increasing complexity of patient needs and stakeholder dynamics within Spain's national health system, this shift emphasizes the importance of aligning MA functions with broader healthcare goals. Effective transformation requires in-depth assessments of stakeholder trends and expectations.
View Article and Find Full Text PDFPatient-Centric Approach to Personalized Electronic Medical Records via QR Code in Japan.
Interact J Med Res
December 2024
Life Science Laboratories, KDDI research atelier, KDDI Research, Inc, Fujimino, Saitama, Japan.
Government policies in the United States and the European Union promote standardization and value creation in the use of FAIR (findability, accessibility, interoperability, and reusability) data, which can enhance trust in digital health systems and is crucial for their success. Trust is built through elements such as FAIR data access, interoperability, and improved communication, which are essential for fostering innovation in digital health technologies. This Viewpoint aims to report on exploratory research demonstrating the feasibility of testing a patient-centric data flow model facilitating semantic interoperability on precision medical information.
View Article and Find Full Text PDFCharacteristics and Outcomes of mHealth Interventions in Psychosis: Systematic Mapping Review.
J Med Internet Res
December 2024
Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.
Background: Mobile health (mHealth) interventions have gained popularity in augmenting psychiatric care for adults with psychosis. Interest has grown in leveraging mHealth to empower individuals living with severe mental illness and extend continuity of care beyond the hospital to the community. However, reported outcomes have been mixed, likely attributed in part to the intervention and adopted outcomes, which affected between-study comparisons.
View Article and Find Full Text PDFThe healthcare system in the United States (US) is complex and often fragmented across national and regional health plans which exhibit substantial variability in benefit design and formulary policies for accessing medications. We propose an access-focused value assessment framework for formulary decision-making for medications to manage immune-mediated inflammatory diseases (IMIDs), where patients are at the center of this framework. Formulary decision-making for IMID medications can be a challenging, even daunting, task with continuously evolving and enhanced treat-to-target goals.
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