Clinical observations of 146 surgical patients have confirmed high informative value of fibrogastroduodenoscopy which could reveal ulcerations in 69% of the patients examined and thus choose the adequate treatment. A thorough study of acid-forming function of the stomach as well as determination of activity of lysosomal enzymes of the gastric juice has shown that hyperacidic state of the mucosa and high activity of alcaline phosphatase of the gastric juice may be considered as risk factors of the formation of acute ulcers.

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