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Degradation products of mangiferin by gamma irradiation with inhibitory effects on NO production. | LitMetric

Degradation products of mangiferin by gamma irradiation with inhibitory effects on NO production.

Biosci Biotechnol Biochem

c Department of Food Science and Biotechnology , Daegu University, Gyeongsan , Korea.

Published: October 2016

AI Article Synopsis

Article Abstract

The xanthone glucoside mangiferin (1) was converted by γ-irradiation into three new compounds, mangiferdiol (2), mangiferinol (3), and isomangiferinol (4). The new compound 2 containing two hydroxymethyl groups instead of a ketone moiety exhibited significantly improved inhibitory activity against nitric oxide production in lipopolysaccharide-stimulated RAW264.7 cells with IC50 value 47.1 ± 1.7 μM, compared to the mother mangiferin.

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Source
http://dx.doi.org/10.1080/09168451.2016.1191335DOI Listing

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