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Top-down curing to construct self-retaining and moisture-pumping double-layered dressing with enhanced antibacterial, hemostatic, and wound healing performances.
Nanoscale
January 2025
Analytical & Testing Center; West China School of Basic Medical Sciences & Forensic Medicine, Sichuan University, Chengdu 610064, China.
Continuous microenvironment modulation is an ongoing challenge in wound dressing, which includes excessive exudate absorption, oxygen delivery, bacterial inhibition and angiogenesis. Herein, we developed an construction strategy to fabricate a self-retaining double-layered wound dressing, where the top layer precursor was composed of Ca-containing polyvinyl butyral (PVB) solution dispersed with hydroxypropyl methylcellulose (HPMC) particles, and the bottom one consisted of sodium alginate (Alg) solution blended with Ag-doped mesoporous bioactive glass powders (Ag-MBG). When in use, both precursors were simultaneously squeezed out from the twin nozzles connected to the individual chambers of a twin-chambered syringe, whereby Ca in the top layer rapidly migrated downwards to crosslink Alg in the bottom layer, leading to the formation of an Alg/Ag-MBG (AA) functional hydrogel for filling an irregular wound.
View Article and Find Full Text PDFAI-Driven Microscopy: Cutting-Edge Approach for Breast Tissue Prognosis Using Microscopic Images.
Microsc Res Tech
January 2025
Artificial Intelligence and Data Analytics (AIDA) lab, CCIS Prince Sultan University, Riyadh, Saudi Arabia.
Microscopic imaging aids disease diagnosis by describing quantitative cell morphology and tissue size. However, the high spatial resolution of these images poses significant challenges for manual quantitative evaluation. This project proposes using computer-aided analysis methods to address these challenges, enabling rapid and precise clinical diagnosis, course analysis, and prognostic prediction.
View Article and Find Full Text PDFApplying the PROMETHEE II, WASPAS, and CoCoSo models for assessment of geotechnical hazards in TBM tunneling.
Sci Rep
January 2025
Faculty of Mining, Petroleum & Geophysics Engineering, Shahrood University of Technology, Shahrood, Iran.
Mechanized tunneling in harsh environments faces many hazards, which can stop tunneling operations for a long time. Due to the high investment volume in tunneling projects, it is imperative to predict and assess the geotechnical hazards. This research has tried to evaluate and introduce the most dangerous section of the Kerman water conveyance tunnel (KWCT) using multi-index decision-making techniques including PROMETHEE II, WASPAS, and CoCoSo models.
View Article and Find Full Text PDFAbsolute Agreement Between Subjective Hand Squeeze and Objective Handgrip Strength in Adults.
J Strength Cond Res
January 2025
Healthy Aging North Dakota (HAND), North Dakota State University, Fargo, North Dakota.
Kieser, J, Langford, M, Stover, E, Tomkinson, GR, Clark, BC, Cawthon, PM, and McGrath, R. Absolute agreement between subjective hand squeeze and objective handgrip strength in adults. J Strength Cond Res 39(1): 16-23, 2025-Despite handgrip strength (HGS) being considered a convenient muscle strength assessment, HGS lacks routine measurement in sports medicine and healthcare settings because barriers such as time and lack of instrumentation may exist.
View Article and Find Full Text PDFAutomated brain tumor recognition using equilibrium optimizer with deep learning approach on MRI images.
Sci Rep
November 2024
Department of Radiological Sciences, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, 21589, Saudi Arabia.
Brain tumours (BT) affect human health owing to their location. Artificial intelligence (AI) is intended to assist in diagnosing and treating complex diseases by combining technologies like deep learning (DL), big data analytics, and machine learning (ML). AI can identify and categorize tumours by analyzing brain imaging approaches like Magnetic Resonance Imaging (MRI).
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