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Epiphyseal Brodie's abscesses represent a rare, slow-progressing form of osteomyelitis that contrasts with the more aggressive types of infection typically seen in bone. These abscesses develop from a low-grade infection and progress gradually, posing unique challenges for treatment due to their proximity to the growth plate and joint structures. While the literature on managing epiphyseal Brodie's abscesses is limited, common treatments include antibiotics and surgical drainage.

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Introduction: Osteomyelitis as a condition in adolescents is difficult to diagnose as it is. In patients with sickle cell disease, the diagnosis is even more difficult due to the occurrence of Vaso occlusive crisis which being the most common acute clinical manifestation of sickle cell disease in bone may mimic osteomyelitis. No single clinical presentation, laboratory result, or imaging finding can definitively distinguish these diagnoses.

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Unusual Sites of Brodie's Abscess and the use of Calcium Sulfate Beads: A Case Series.

J Orthop Case Rep

November 2024

Department of Orthopaedic Surgery, AIIMS Kalyani, Kalyani, West Bengal, India.

Introduction: Brodie's abscess is one type of subacute osteomyelitis without any sequestrum or any systemic illness. Thorough debridement and removal of sclerotic rim are the mainstay of the treatment. Antibiotic-impregnated calcium sulfate (AICS) beads act as osteoconductive and at the same time, it maintains high antibiotic concentration locally.

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Article Synopsis
  • Brodie's abscess is a specific type of subacute osteomyelitis often mistaken for tumors; the study reviews five cases located in the distal tibia.
  • All patients experienced chronic ankle pain and swelling without serious systemic symptoms, and initial tests usually showed normal inflammatory markers.
  • The abscesses were treated with curettage and bone grafting, with no detected infections, distinguishing them from bone tumors through unique clinical and radiographic features.
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