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| http://dx.doi.org/10.1093/omcr/omw038 | DOI Listing |
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Benzodiazepine agonist treatment for patients with benzodiazepine dependence undergoing opioid agonist treatment: a study protocol for the randomized controlled trial BMX-BAR.
Trials
January 2025
Department of Addiction Medicine, Haukeland University Hospital, Bergen, Norway.
Background: There is a lack of knowledge on effective treatment methods for comorbid benzodiazepine dependence in populations undergoing opioid agonist treatment (OAT). Tapering and discontinuation of benzodiazepines has long been considered the standard treatment, even though there is limited evidence for this practice. There is also limited research on benzodiazepine agonist treatment; however, peer and clinical experiences indicate that such approaches may be beneficial for a subgroup of the patients with long-lasting benzodiazepine dependence not responding to other treatment approaches.
View Article and Find Full Text PDFHarm reduction and its monitoring in Europe, from EMCDDA to EUDA.
Harm Reduct J
December 2024
EUDA, Praça Europa 1, Cais do Sodré, 1249-289, Lisbon, Portugal.
Background: Harm Reduction, conceptualized by Russell Newcombe in the late 1980s, has revolutionized how drug use, individuals who use drugs, and drug policies are understood globally. Emerging from the HIV/AIDS crisis, Harm Reduction sought to address the dire rates of drug-related infections and the overwhelming burden on healthcare providers. Early initiatives, such as Opioid Substitution Treatment (OST) and needle exchange programs, were met with resistance but gradually established new standards of care, transforming attitudes toward people who use drugs and prioritizing human-centered, rather than solely medical, approaches.
View Article and Find Full Text PDFPrevalence of new psychoactive substances and drugs of abuse in the hair of individuals diagnosed with substance use disorder: Polydrug and emerging pattern of consumption.
J Forensic Sci
December 2024
Department of Medical and Surgical Sciences, Unit of Legal Medicine, University of Bologna, Bologna, Italy.
People diagnosed with substance use disorder (SUD) might represent a high-risk subpopulation for New Psychoactive Drugs (NPS) consumption, and hair analysis offers a unique perspective to assess drug prevalence in this population. The present study aims to assess the prevalence of NPS and their co-consumption with traditional drugs of abuse (DoA) in individuals diagnosed with SUD. Hair samples from patients under care at the addiction treatment service of Bologna, Italy, for a diagnosed SUD, were collected during 2023 and analyzed by ultra-high-performance liquid chromatography-mass spectrometry (UHPLC-MS/MS), using a previously validated method.
View Article and Find Full Text PDFImpact of 'street' benzodiazepines on drug-related deaths in England, Wales and Northern Ireland.
Drug Alcohol Rev
November 2024
Institute of Pharmaceutical Science, King's College London, London, UK.
Introduction: 'Street' benzodiazepines (BZD) are structurally and pharmacologically related to BZDs licensed for human use. In this study we investigated how street BZDs contribute to overall BZD use and death prevalences in England, Wales and Northern Ireland.
Methods: Data were analysed from deaths reported to the National Programme on Substance Use Mortality with post-mortem BZD detections (1999-2021), BZDs seized from music festivals (2017-2021) and drug samples with BZD detections submitted to Welsh Emerging Drugs and Identification of Novel Substances (WEDINOS) (2017-2021).
Breaking barriers: a qualitative exploration of healthcare access for crack cocaine users in Limerick.
BMC Health Serv Res
November 2024
School of Medicine, University of Limerick, Castletroy, Limerick, Ireland.
Article Synopsis
- Crack cocaine use in Ireland has risen since the early 2000s, with limited research on barriers to accessing available health and social services for users, prompting a dual-perspective investigation involving both service users and providers.
- Utilizing qualitative methodology, the study identified significant barriers such as inadequate support for individuals with dual diagnosis, stigma from healthcare providers, and systemic issues like distrust and stringent requirements that prevent timely access to care.
- The conclusion emphasizes the need for a tailored approach to improve healthcare access for crack cocaine users through collaboration among providers, partnerships with educational and community organizations, and necessary policy changes.
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