Study Design: Disk material removed (DMR) during L4-5 and L5-S1 transforaminal lumbar interbody fusion (T-LIF) surgery was compared to the corresponding bone graft (BG) volumes inserted at the time of fusion. A novel BG delivery tool (BGDT) was used to apply the BG. In order to establish the percentage of DMR during T-LIF, it was compared to DMR during anterior diskectomy (AD). This study was performed prospectively.
Summary Of Background Data: Minimal information is available as to the volume of DMR during a T-LIF procedure, and the relationship between DMR and BG delivered is unknown. BG insertion has been empiric and technically challenging. Since the volume of BG applied to the prepared disk space likely impacts the probability of arthrodesis, an investigation is justified.
Methods: A total of 65 patients with pathology at L4-5 and/or L5-S1 necessitating fusion were treated with a minimally invasive T-LIF procedure. DMR was volumetrically measured during disk space preparation. BG material consisting of local autograft, BG extender, and bone marrow aspirate were mixed to form a slurry. BG slurry was injected into the disk space using a novel BGDT and measured volumetrically. An additional 29 patients who were treated with L5-S1 AD were compared to L5-S1 T-LIF DMR to determine the percent of T-LIF DMR relative to AD.
Results: DMR volumes averaged 3.6±2.2 mL. This represented 34% of the disk space relative to AD. The amount of BG delivered to the disk spaces was 9.3±3.2 mL, which is 2.6±2.2 times the amount of DMR. The BGDT allowed uncomplicated filling of the disk space in <1 minute.
Conclusion: The volume of DMR during T-LIF allows for a predictable volume of BG delivery. The BGDT allowed complete filling of the entire prepared disk space. The T-LIF diskectomy debrides 34% of the disk relative to AD.
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http://dx.doi.org/10.2147/MDER.S100098 | DOI Listing |
J Clin Med
January 2025
Department of Neurosurgery, Montefiore Medical Center, Bronx, NY 10461, USA.
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January 2025
Hainan Key Laboratory of Storage and Processing of Fruits and Vegetables, Agricultural Products Processing Research Institute, Chinese Academy of Tropical Agricultural Sciences, Zhanjiang 524001, China.
This study aimed to determine the chemical composition of five essential oils (LEOs) using the gas chromatography-mass spectroscopy technique and to assess their antibacterial activity against four marine species, including , , , and . Sensitivity tests were performed using the disk diffusion and serial dilution methods. The results showed that all five LEOs exhibited antibacterial activity against the four tested marine species.
View Article and Find Full Text PDFBMC Oral Health
January 2025
School of Dentistry, Complutense University of Madrid, Madrid, 28040, Spain.
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Comput Methods Programs Biomed
December 2024
CenBRAIN Neurotech Center of Excellence, School of Engineering, Westlake University, Zhejiang, Hangzhou, China.
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Sci Rep
January 2025
Key Laboratory of Gas and Fire Control for Mines, Ministry of Education, Xuzhou, 221116, China.
Confined space fires could easily cause serious casualties and property damage, and foam is an effective means of preventing confined space fires. The existing foam generator does not have both momentum and foam expansion rate (FER) and is poorly suited to confined spaces. In order to develop a foam generator suitable for confined space fire protection, an in-depth analysis of the physical foaming characteristics of self-suction foam is required, and the structure of the foam generator is optimized accordingly.
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