Low-grade nasopharyngeal papillary adenocarcinoma is an extremely rare tumor, with only a limited number of cases reported in the literature. Some published studies have paid more attention to the clinicopathological features of nasopharyngeal adenocarcinoma, while little effort has been made to study the optimal therapeutic strategies. We report about a woman diagnosed with low-grade nasopharyngeal papillary adenocarcinoma. She received the treatment approach that combined transnasal endoscopic surgery to remove the lesion with postoperative radiotherapy for nasal cavity. There was no evidence of recurrence after 4 months of surgery, and further follow-up is being continued. Through this example, we wanted to explore the optimal therapeutic strategies for primary nasopharyngeal adenocarcinomas.
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http://dx.doi.org/10.2147/OTT.S100447 | DOI Listing |
Am J Surg Pathol
January 2025
Department of Pathology, Eye & ENT Hospital, Fudan University.
Animals (Basel)
May 2024
Department of Veterinary Clinical Sciences, Jockey Club College of Veterinary Medicine and Life Sciences, City University of Hong Kong, Hong Kong.
This study aimed to characterize and describe the different lymphoma types and anatomical forms in cats in Hong Kong. The clinical and histopathological data of cats diagnosed with lymphoma by cytology and/or histopathology were collected from a large diagnostic laboratory in Hong Kong. In total, 444 cats were diagnosed with lymphoma over four years (2019-2022).
View Article and Find Full Text PDFFront Oncol
May 2024
Department of Otorhinolaryngology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Hyalinizing clear cell carcinomas (HCCCs) are infrequent, malignant tumors characterized by their low-grade nature. They typically originate from minor salivary glands. However, these tumors can potentially emerge in any location with minor salivary glands, including the nasopharynx.
View Article and Find Full Text PDFInt J Surg Case Rep
June 2024
Otolaryngology, Head & Neck Surgery and Microvascular Reconstructive Surgery, Saudi Arabia; Department of Otolaryngology-Head and Neck Surgery, Security Forces Hospital, Riyadh, Saudi Arabia.
Introduction And Importance: Polymorphous low-grade adenocarcinoma (PLGA) is a rare neoplasm arising from minor salivary glands, representing approximately 3 % of head and neck tumors. The clinical presentation of PLGA is defined as a painless, slow-growing tumor, mostly occurring in the palate. We report a case of PLGA with a rare presentation.
View Article and Find Full Text PDFFront Immunol
April 2024
Surgical Oncology Clinic, Institute of Oncology, Poznan University of Medical Sciences, Poznan, Poland.
Oncolytic virus (OV) therapy has emerged as a promising frontier in cancer treatment, especially for solid tumours. While immunotherapies like immune checkpoint inhibitors and CAR-T cells have demonstrated impressive results, their limitations in inducing complete tumour regression have spurred researchers to explore new approaches targeting tumours resistant to current immunotherapies. OVs, both natural and genetically engineered, selectively replicate within cancer cells, inducing their lysis while sparing normal tissues.
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