Consensus treatment for herpetic meningoencephalitis is intravenous aciclovir but no guidelines are available for alternative treatment in case of renal failure induced by aciclovir. We report to the best of our knowledge, the first case of herpetic meningoencephalitis treated with success by ganciclovir.
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http://dx.doi.org/10.1080/1120009X.2016.1195070 | DOI Listing |
Clin Case Rep
January 2025
Department of Otorhinolaryngology Centre Hospitalier Régional Universitaire de Nancy, Hôpitaux de Brabois Vandœuvre-Lès-Nancy France.
After surgery involving cranial nerves and more generally the central nervous system, nonbacterial meningitis should raise suspicion of herpes simplex virus type 1 reactivation. No time should be wasted in diagnosis and treatment; therefore, a polymerase chain reaction testing on cerebrospinal fluid should be systematic in this situation, without neglecting to consider other differential diagnoses.
View Article and Find Full Text PDFDiscoveries (Craiova)
September 2024
Department of Microbiology, King George's Medical University Lucknow, India.
Herpes simplex virus (HSV) encephalitis is a life-threatening consequence of HSV infection of the central nervous system. Early antiviral therapy is most effective, necessitating prompt diagnosis. We report a case of atypical HSV encephalitis.
View Article and Find Full Text PDFMikrobiyol Bul
October 2024
University of Health Sciences, Dr. Behçet Uz Pediatric Diseases and Surgery Training and Research Hospital, Clinic of Pediatric Infectious Diseases, İzmir, Türkiye.
Mol Neurobiol
December 2024
Department of Neurology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Virus encephalitis (VE), recognized as one of the common kinds of central nervous system (CNS) diseases after virus infection, has a surprising correlation with autoimmune encephalitis (AE) when autoimmune antibodies emerge in cerebrospinal fluid (CSF) or serum. Herpes simplex virus and Epstein-Barr virus are the most critical agents worldwide. By molecular mimicry, herpes viruses can invade the brain directly or indirectly.
View Article and Find Full Text PDFClin Microbiol Infect
December 2024
Department of Infectious Diseases, Aalborg University Hospital, 9000 Aalborg, Denmark; Department of Clinical Medicine, Aalborg University, 9000 Aalborg, Denmark; European Society of Clinical Microbiology and Infectious Diseases Study Group of Infections of the Brain (ESGIB).
Background: Infectious encephalitis poses a global health challenge with a high mortality and severe neurological consequences in survivors. Emerging pathogens and outbreaks are reshaping the patterns of the disease.
Objective: To understand the current epidemiology for improving prevention, diagnosis, and treatment.
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