Research Institute of Sport Science, University of Physical Education, Budapest, Hungary; Institute of Sport Sciences and Physical Education, University of Pecs, Pecs, Hungary. Electronic address:
Published: October 2016
AI Article Synopsis
Article Abstract
There is an increasing volume of data connecting capacity to respond to exercise training with quality of life and aging. In this study, we used a rat model in which animals were selectively bred for low and high gain in running distance to test t whether genetic segregation for trainability is associated with brain function and signaling processes in the hippocampus. Rats selected for low response (LRT) and high response training (HRT) were randomly divided into control or exercise group that trained five times a week for 30 min per day for three months at 70% VO2max. All four groups had similar running distance before training. With training, HRT rats showed significantly greater increases in VO2max and running distance than LRT rats (p < 0.05). On the reverse Morris Maze test HRT-trained rats outperformed HRT control ones. Significant difference was noted between LRT and HRT groups in redox milieu as assessed by levels of reactive oxygen species (ROS), carbonylation of proteins, nNOS and S-nitroso-cysteine. Moreover the silent information regulator 1 (SIRT1), brain-derived neurotrophic factor (BDNF), ratio of phospho and total cAMP-response element binding protein (CREB), and apoptotic index, also showed significant differences between LRT and HRT groups. These findings suggest that aerobic training responses are not localized to skeletal muscle, but differently involve signaling processes in the brain of LRT and HRT rats.
Running is a popular form of physical activity, yet it comes with risks, including running-related injuries (RRIs). This cohort study aimed to use self-reported baseline data on running experience, weekly running frequency, greatest running distance in 1 week, and running program to investigate if certain adult runners were more likely to sustain RRI than others. Runners, aged ≥ 18 years, familiar with the English language and using a Garmin watch to track their running were included.
Supercritical-dense phase CO pipeline transportation has been proven to have excellent economic and safety benefits for long-distance CO transportation in large-scale. Hydrates are easily generated in the high-pressure and low-temperature sections, resulting in blockage, so it is necessary to build the prediction model for hydrate formation in the long-distance CO pipeline transportation. In the prediction model of hydrate formation of our work, the phase equilibrium was determined by the Chen-Guo model, and the lateral growth of hydrate was calculated by the comprehensive growth model, and the hydrate growth was estimated by analogy with the condensation process.
The study aim was to compare the external load during varying microcycles (M1-M4 during pre-season and M5 during the in-season) in elite female Portuguese soccer players and to describe external load variations between differing Ms. Fourteen first-team players participated in the study (age 23.29 ± 3.
