Stopping Manual and Vocal Actions in Tourette's Syndrome.

J Neuropsychiatry Clin Neurosci

From the Dept. of Neurology, Vanderbilt University, Nashville, Tenn. (SAW, DOC, KEK, NCvW); the Dept. of Psychology, University of Amsterdam, Amsterdam, the Netherlands (WPMvdW); and Amsterdam Brain and Cognition, University of Amsterdam, Amsterdam, the Netherlands (WPMvdW).

Published: June 2016

Evidence that Tourette's syndrome (TS) disrupts inhibitory motor control is highly mixed. The authors investigated inhibitory control of manual and vocal actions in young adults with relatively uncomplicated, persistent TS. Both TS and control groups showed similar response latencies when executing manual and vocal reactions, but individuals with TS were slower at stopping their manual and vocal responses. While alterations in inhibitory motor control may not be a generalizable phenomenon in TS, these results add to an emerging literature suggesting that individuals with relatively uncomplicated TS, whose symptoms persist into adulthood, show disruption to inhibitory control mechanisms.

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Source
http://dx.doi.org/10.1176/appi.neuropsych.15110387DOI Listing

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