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Ameliorative Potential of Resveratrol on Kidney Toxicities Following Adjuvant Treatment with Antiretroviral Drugs in Male Wistar Rats.
Arch Razi Inst
June 2024
Department of Anatomy, Faculty of Basic Medical Sciences, Federal University Oye-Ekiti, Oye-Ekiti, Ekiti State, Nigeria.
Prolonged use of antiretroviral agents has been clearly associated with nephrotoxicity, suggesting deterioration of renal function in patients receiving Highly Active Antiretroviral Therapy (HAART). The present study was designed to investigate the therapeutic efficacy of resveratrol (RV) in the treatment toxins-induced renal impairment. Twenty-four adult male Wistar rats weighing 70-90 g were divided into four groups and subjected to the following treatments: Control A (distilled water), B (HAART), C (RV-2.
View Article and Find Full Text PDFThe Effects of Different Hygiene Instrumentations on Titanium Implant Fixture Surfaces.
Cureus
November 2024
School of Dental Sciences, Universiti Sains Malaysia, Kota Bharu, MYS.
Background and objective Applying different hygiene tools for implant maintenance alters surface configurations, impacting bacterial adhesion on titanium implant surfaces and potentially leading to peri-implant diseases. This study aimed to assess the alterations in surface topography of titanium implant fixtures after utilizing hygiene instruments such as airflow; erbium, chromium-doped: yttrium, scandium, gallium, and garnet (Er, Cr: YSGG) laser; and titanium brush, under scanning electron microscope (SEM) observation. Materials and methods We employed an experimental laboratory study design for this research, involving 20 MegaGen ST titanium implant fixtures (MegaGen Implant Co.
View Article and Find Full Text PDFAssociation between serum albumin levels at admission and clinical outcomes in pediatric intensive care units: a multi-center study.
BMC Pediatr
December 2024
Department of Pediatric Intensive Care, Faculty of Medicine, Cukurova University, Adana, Turkey.
Background: Albumin, a vital component in regulating human blood oncotic pressure, plays an important role in the prediction of prognosis in pediatric patients.Previous research identified significant differences in serum albumin levels of healthy and critically ill children.
Methods: The present study aims to investigate the correlation between albumin levels measured during pediatric intensive care unit(PICU) admission and clinical outcomes.
Construction of Nanohydroxyapatite/Poly(sodium lipoate)-Based Bioactive Hydrogels for Cranial Bone Regeneration.
Biomacromolecules
December 2024
School of Chemistry, Xi'an Jiaotong University, Xi'an 710049, China.
Persistent oxidative stress following bone defects significantly impedes the repair of bone tissue. Designing an antioxidative hydrogel with a suitable mechanical strength can help alter the local microenvironment and promote bone defect healing. In this work, α-lipoic acid (LA), a natural antioxidant small molecule, was chemically cross-linked with lipoic acid-functionalized poly(ethylene glycol) (PEG, = 6k or 10k) in sodium bicarbonate solution, to prepare LA-PEG hydrogels (LP, = 6k or 10k).
View Article and Find Full Text PDFSynergetic degradation of PFOS by HALT conditions enhanced by Fe-based amorphous alloys.
J Hazard Mater
December 2024
State Key Laboratory of Clean Energy Utilization, Zhejiang University, Hangzhou 310027, China.
Global concern over per- and polyfluoroalkyl substances (PFASs), especially perfluorooctane sulfonate (PFOS), disposal prompts the search for effective degradation methods. Subcritical water hydrothermal treatment shows promise but suffers from unclear degradation pathways, hindering engineering application design due to unknown intermediate products. This study introduces Fe-based amorphous alloy to enhance the subcritical water hydrothermal degradation of PFOS, achieving a degradation rate of approximately 85 % under optimized conditions of 325 °C and 1 M sodium bicarbonate (NaHCO₃), compared to 56 % without the alloy.
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