Traumatic brain injury (TBI) is a leading cause of death and disability worldwide. A bright, renal-excreted, and biocompatible near-infrared II fluorophore for in vivo imaging of TBI is designed. A transient hypoperfusion in the injured cerebral region, followed by fluorophore leakage, is observed. NIR-II fluorophores can provide noninvasive assessment of TBI.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5293734 | PMC |
| http://dx.doi.org/10.1002/adma.201600706 | DOI Listing |
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