AI Article Synopsis
- The work proposes a new method for the T2 - T2 Exchange NMR experiment by using a fixed number of π pulses, acting as a short T2-filter rather than varying them.
- By adjusting the storage time, this approach enables a series of 1D T2 distribution measurements that highlight migration dynamics and relaxation effects.
- This innovation leads to shorter experiment times and enhanced signal quality, facilitating a detailed analysis of exchange dynamics and relaxation processes, termed T2-Filtered T2 - T2 Exchange NMR (T2 F-TREx).
Article Abstract
This work introduces an alternative way to perform the T2 - T2 Exchange NMR experiment. Rather than varying the number of π pulses in the first CPMG cycle of the T2 - T2 Exchange NMR pulse sequence, as used to obtain the 2D correlation maps, it is fixed and small enough to act as a short T2-filter. By varying the storage time, a set of 1D measurements of T2 distributions can be obtained to reveal the effects of the migration dynamics combined with relaxation effects. This significantly reduces the required time to perform the experiment, allowing a more in-depth study of exchange dynamics and relaxation processes with improved signal-to-noise ratio. These aspects stand as basis of this novel experiment, T2-Filtered T2 - T2 Exchange NMR or simply T2 F-TREx.
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| http://dx.doi.org/10.1063/1.4951712 | DOI Listing |
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