This study analyzes driver injury severities for single-vehicle crashes occurring in rural and urban areas using data collected in New Mexico from 2010 to 2011. Nested logit models and mixed logit models are developed in order to account for the correlation between severity categories (No injury, Possible injury, Visible injury, Incapacitating injury and fatality) and individual heterogeneity among drivers. Various factors, such as crash and environment characteristics, geometric features, and driver behavior are examined in this study. Nested logit model and mixed logit model reveal similar results in terms of identifying contributing factors for driver injury severities. In the analysis of urban crashes, only the nested logit model is presented since no random parameter is found in the mixed logit model. The results indicate that significant differences exist between factors contributing to driver injury severity in single-vehicle crashes in rural and urban areas. There are 5 variables found only significant in the rural model and six significant variables identified only in the urban crash model. These findings can help transportation agencies develop effective policies or appropriate strategies to reduce injury severity resulting from single-vehicle crashes.
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http://dx.doi.org/10.1016/j.aap.2016.03.026 | DOI Listing |
Traffic Inj Prev
January 2025
School of Traffic & Transportation Engineering, Changsha University of Science & Technology, Changsha, Hunan, China.
Objective: This study aims to investigate the causes of 2-vehicle collisions involving an autonomous vehicle (AV) and a conventional vehicle (CV). Prior research has primarily focused on the causes of crashes from the perspective of AVs, often neglecting the interactions with CVs.
Method: To address this limitation, the study proposes a classification framework for crash causation patterns in 2-vehicle collisions involving an AV and a CV, considering their interactions.
Infect Drug Resist
January 2025
Tuberculosis Diagnosis and Treatment Center, Hangzhou Red Cross Hospital, Hangzhou, Zhejiang Province, People's Republic of China.
Background: Immune checkpoint inhibitors (ICIs) have emerged as the first-line treatment for driver-negative advanced non-small cell lung cancer (NSCLC). However, there is uncertainty regarding the availability and timing of ICI initiation in patients with NSCLC combined with pulmonary tuberculosis (TB). Additionally, the implementation of dual therapy for anti-TB and anti-tumor treatment poses significant challenges in terms of avoiding drug-drug interactions and reducing adverse reactions during clinical diagnosis and treatment.
View Article and Find Full Text PDFInt J Biol Macromol
January 2025
College of Chemistry and Life Science, Beijing University of Technology, Beijing 100124, China; Beijing Institute of Radiation Medicine, Beijing 100850, China; School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou 510006, China. Electronic address:
Neuroinflammation is a key driver of neurological disorders. Evodiamine (EVO), an alkaloid from the traditional Chinese herb Evodia rutaecarpa, possesses potent biological activities, notably anticancer and anti-inflammatory effects. This study investigates EVO's potential to attenuate LPS-induced neuroinflammation, focusing on identifying its therapeutic targets and mechanisms of action.
View Article and Find Full Text PDFJ Wound Care
January 2025
Alice Lee Centre for Nursing Studies, Yong Loo Lin School of Medicine, National University of Singapore, Clinical Research Centre, Singapore.
Objective: There is little use of maggot debridement therapy (MDT) worldwide, albeit there is much literature supporting its benefits and effectiveness for hard-to-heal (chronic) wounds. Hard-to-heal wounds are becoming ever more prevalent and MDT can play a pivotal role in wound care management. This underuse can be associated with patients' perceptions and experiences of MDT.
View Article and Find Full Text PDFAccid Anal Prev
January 2025
USDOT Center for Advanced Multimodal Mobility Solutions and Education, United States; Department of Civil and Environmental Engineering, University of North Carolina at Charlotte, United States. Electronic address:
Speeding crashes remain high injury severities after the stay-at-home order in California, highlighting a need for further investigation into the fundamental cause of this increment. To systematically explore the temporal impacts of the stay-at-home order on speeding behaviors and the corresponding crash-injury outcomes, this study utilizes California-reported single-vehicle speeding crashes on freeways (access-controlled) and non-freeways (non-access-controlled) before, during, and after the order. Significant injury factors and in-depth heterogeneity across observations are identified by random parameter logit models with heterogeneity in means and variances.
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