Background: Peracetic acid sporicidal wipes have been shown to be an effective disinfectant, but in controlled test environments. Their high cost may restrict use.
Aims: This pilot study investigated the efficacy and compared the costs of routine universal use of peracetic acid sporicidal wipes versus sporicidal quaternary ammonium compound and alcohol wipes in the disinfection of a hospital environment.
Methods: The routine universal use of peracetic acid wipes (Clinell Sporicidal; GAMA Healthcare Ltd, London, UK) was allocated to a study ward, whereas the control ward continued with the use of quaternary ammonium compound wipes (Tuffie 5; Vernacare, Bolton, UK) and alcohol wipes (PDI Sani-Cloth 70; PDI, Flint, UK). Twenty high-touch areas in the 2 wards were sampled for the presence of indicator organisms. The weekly detection rates of indicator organisms and weekly healthcare associated infection (HCAI) rates in the 2 wards were compared and examined for decreasing trends over the trial period.
Results: The detection rates of indicator organisms and HCAI rates were not significantly different in the 2 wards, and did not decrease significantly over the trial period. However, the peracetic acid wipes seem to be more effective against gram-negative organisms but at a significantly higher cost.
Conclusions: Further prospective studies are needed to assess the cost-effectiveness of peracetic acid wipes.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.ajic.2016.03.046 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
A sterilization method for human decellularized vaginal matrices.
Sci Rep
December 2024
Department of Medical Microbiology and Infection Prevention, Amsterdam UMC - Location AMC, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands.
Vaginal reconstruction is necessary for various congenital and acquired conditions, including vaginal aplasia, trauma, tumors, and gender incongruency. Current surgical and non-surgical treatments often result in significant complications. Decellularized vaginal matrices (DVMs) from human tissue offer a promising alternative, but require effective sterilization to ensure safety and functionality.
View Article and Find Full Text PDFRemoval of sulfamethoxazole by Fe(III)-activated peracetic acid combined with ascorbic acid.
Environ Technol
December 2024
School of Environmental Science and Engineering, Southwest Jiaotong University, Chengdu, People's Republic of China.
Ascorbic acid (AA) was used as a reducing agent to improve the Fe(III)-activated peracetic acid (PAA) system for the removal of sulfamethoxazole (SMX) in this work. The efficiency, influencing factors and mechanism of SMX elimination in the AA/Fe(III)/PAA process were studied. The results exhibited that AA facilitated the reduction of Fe(III) to Fe(II) and subsequently improved the activation of PAA and HO.
View Article and Find Full Text PDFDecontamination Validation of the BSL-4 Chemical Disinfectant Deluge Shower System.
Appl Biosaf
December 2024
National Microbiology, Public Health Agency of Canada, Winnipeg, Canada.
Introduction: Positive pressure breathing-air-fed protective suits are used in biosafety level 4 (BSL-4) containment laboratories as personal protective equipment to protect workers from high-consequence pathogens. However, even with the use of primary containment devices, the exterior surfaces of these suits could potentially become contaminated with those pathogens and result in their inadvertent removal from containment. To address the risk of such pathogens escaping from containment via contaminated protective suits, these suits are decontaminated in a disinfectant chemical shower situated in an anteroom prior to exiting the BSL-4 laboratory.
View Article and Find Full Text PDFDetermining the Efficacy of Chemicals for the Inactivation of Liquid Waste Containing Gram-Positive Bacteria of Risk Group 2.
Appl Biosaf
December 2024
Neuroinfection Laboratory Institute for Infectious Diseases, University of Bern, Bern, Switzerland.
Background: Inactivation of infectious liquid waste can be performed by different means, including autoclaving or chemical inactivation. Autoclaving is most widely used, but cannot always be implemented, so that chemical inactivation is a possible alternative. However, its efficacy has to be proven by in-house validation.
View Article and Find Full Text PDFOptimization of the preparation of a spiny spore high-concentrated Aspergillus brasiliensis suspension.
Lett Appl Microbiol
December 2024
Cantel Medical Italy, a STERIS Company, Via Laurentina, 169, 00071 Pomezia, Italy.
This work aimed to improve some steps of the existing guidelines of the European Standards to obtain an Aspergillus brasiliensis ATCC 16404 spore suspension with >75% spiny spores without mycelia and a concentration of at least 1.5×108 CFU ml-1. Several manufacturers' combinations "strain/medium" were assessed in terms of yield of spiny spores.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!