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Long-term efficacy and safety of avatrombopag in Chinese children with primary immune thrombocytopenia: A real-world observational study.
Br J Haematol
January 2025
Hematology Department, Beijing Children's Hospital, Hemophilia Comprehensive Care Center, National Center for Children's Health, Capital Medical University, Beijing, China.
Avatrombopag is a newly approved thrombopoietin receptor agonist for second-line treatment of chronic immune thrombocytopenia (ITP) in adults. Our previous study showed its efficacy and safety in a small sample of paediatric ITP patients. However, large samples and long-term data are still lacking.
View Article and Find Full Text PDFPrevalence and risk factors of long COVID-19 persisting for 2 years in Hainan Province: a population-based prospective study.
Sci Rep
January 2025
Department of Gastroenterology, The Second Affiliated Hospital of Hainan Medical University, Yehai Avenue, #368, Longhua District, Haikou, 570216, Hainan Province, China.
Coronavirus disease 2019 (COVID-19) can lead to persistent symptoms, sequelae, and other medical complications that may last for weeks or months after recovery. The aim of the study is to assess the prevalence and risk factors of long COVID-19 persisting for 2 years in Hainan Province, China, to aid in its recognition, prevention, and treatment. Between July and August 2022, 960 individuals with confirmed SARS-CoV-2 infection in Hainan, China, were recruited.
View Article and Find Full Text PDFTransgender in Detention: Victimization Experiences in Immigration Facilities.
Transgend Health
December 2024
School of Teacher Education and Leadership, Utah State University, Logan, Utah, USA.
Purpose: In this article, we describe and illustrate the victimization experiences of transgender immigrants in the U.S. detention system.
View Article and Find Full Text PDFEvidence-Based Strategies to Minimize Unnecessary Primary Cesarean Sections: A Comprehensive Review.
Cureus
November 2024
Department of Obstetrics and Gynaecology, Batterjee Medical College for Science and Technology, Jeddah, SAU.
The increase in cesarean section (CS) rates, whether they are classified as unnecessary or elective, has globally raised significant concerns due to the associated risks involving maternal and neonatal outcomes. Although CS can be a lifesaving operation in specific medical cases, its overuse is exposing mothers and neonates to complications like hemorrhage, infections, and long-term consequences such as uterine scarring, infertility, and future pregnancy problems. The contributing factors include maternal preferences for convenience, fear of labor, and financial incentives within the healthcare systems that favor surgical interventions.
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Sci Rep
December 2024
School of Mechanical and Electrical Engineering, Qiqihar University, Qiqihar, 161006, China.
A prediction model of the pig house environment based on Bayesian optimization (BO), squeeze and excitation block (SE), convolutional neural network (CNN) and gated recurrent unit (GRU) is proposed to improve the prediction accuracy and animal welfare and take control measures in advance. To ensure the optimal model configuration, the model uses a BO algorithm to fine-tune hyper-parameters, such as the number of GRUs, initial learning rate and L2 normal form regularization factor. The environmental data are fed into the SE-CNN block, which extracts the local features of the data through convolutional operations.
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