The sequential extraction of peony seed dreg polysaccharides (PSDP) with hot buffer (HBSS), chelating agent (CHSS), dilute alkaline (DASS) and concentrated alkaline (CASS) yielded four different polysaccharide fractions. Based on their absorptions at 3600-3200cm(-1) and 1200-800cm(-1), these fractions were confirmed to be polysaccharides. The properties of four PSDPs displayed some slight differences. The CASS showed the highest peak temperature and endothermic enthalpy. The emulsifying activity and emulsifying stability of four PSDPs exhibited a dose-dependent pattern; HBSS showed the highest emulsifying activity, and CHSS displayed the longest emulsifying stability. The four PSDPs also exhibited wide variations in their antioxidant activities. For example, i) CASS showed the highest DPPH radical scavenging activity, reducing power and ABTS radical scavenging activity; ii) HBSS exhibited the highest hydroxyl radical scavenging activity, and iii) CHSS displayed the higher ferrous ions chelating ability than others.
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http://dx.doi.org/10.1016/j.ijbiomac.2016.05.082 | DOI Listing |
Chem Biodivers
January 2025
Yili Normal University, School of Chemisty and Chemical Engineering, 448 Jiefang West Road, Yining City, Xinjiang, 835000, Yining, CHINA.
In this study, we optimal the ultrasound-assisted ionic liquid extraction (UAILE) process of polysaccharides from Crataegus songarica K. Koch fruits. The optimal conditions determined were: ultrasonic power of 400 W, temperature of 79 ℃, extraction time of 78 min, Ethylammonium dodecyl sulfate (EADS) concentration of 1.
View Article and Find Full Text PDFFront Chem
December 2024
Department of Algology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Introduction: Compression of the nerve root by a lumbar disc herniation can cause radiating pain in the lower limbs, and the nerve root decompression treatment may leave some patients with motor dysfunction and reduced sensory function. Studies have shown that nerve growth factor (NGF) can promote nerve growth and repair, but high doses, long duration, and immune response have become bottlenecks of its clinical application.
Methods: To overcome this obstacle, we developed Prussian blue (PBs) nanoparticles with the bio-delivery function and antioxidant effects of nanoenzymes.
ACS Biomater Sci Eng
January 2025
Research Center for Nano-Biomaterials, Analytical and Testing Center, Sichuan University, Chengdu 610064, PR China.
Oxidative stress induced by reactive oxygen species (ROS) can adversely affect tissue repair, whereas endowing biomaterials with antioxidant activity can improve the in vivo microenvironment, thereby promoting angiogenesis and osteogenesis. Accordingly, this study utilized epigallocatechin-3-gallate (EGCG), a material known for its reducing properties, oxidative self-polymerization capability, and strong binding characteristics, to modify a bioactive core-shell fibrous membrane (10RP-PG). Compared to the 10RP-PG fibrous membrane, the EGCG-modified fibrous membrane (E/10RP-PG) exhibited superior hydrophilicity, excellent cell adhesion, and compatibility.
View Article and Find Full Text PDFInt J Biol Macromol
December 2024
College of Food Science and Light Industry, Nanjing Tech University, Nanjing 211816, PR China; State Key Laboratory of Materials-Oriented Chemical Engineering, Nanjing Tech University, Nanjing 211816, PR China. Electronic address:
Hyaluronic acid (HA) exhibits various biological activities and functions, mainly governed by its molecular weight (M). Traditional HA degradation methods encounter challenges such as environmental pollution and high costs. Thus, developing a safe cell factory with an efficient regulation strategy for one-step production of specific M HA has attracted significant research interest.
View Article and Find Full Text PDFInt J Biol Macromol
December 2024
Department of Chemistry, Himachal Pradesh University, Shimla 171005, India.
The versatile properties of carbohydrate polymers make them a relevant, promising precursor to design innovative materials for use in biomedical applications. Recent research mainly focuses on the development of the polysaccharide based functional materials. Hydrogel derived materials are a source of great motivation for the development of drug delivery (DD) carriers with inherent therapeutic potential.
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