AI Article Synopsis
- Uterine leiomyosarcoma (LMS) can spread within the abdominal cavity, leading to a unique condition called abdominal sarcomatosis, which necessitates radical surgical intervention for better survival outcomes.
- A case is presented of a 51-year-old woman who underwent extensive laparoscopic surgery, including hysterectomy and omentectomy, due to diffuse abdominal sarcomatosis from LMS.
- The patient has been closely monitored every few months with advanced imaging and subsequent laparoscopies, successfully managing disease recurrence, and remains healthy 5 years post-diagnosis, highlighting the effectiveness of laparoscopic techniques in controlling this cancer.
Article Abstract
Uterine leiomyosarcoma (LMS) in some cases may disseminate through the abdominal cavity, without extra-abdominal spreading, determining a condition of abdominal sarcomatosis, which represents a peculiar situation. Only radical surgical removal offers a chance of long-term survival in such cases of LMS. Here we describe a case of diffuse abdominal sarcomatosis from uterine LMS in a 51-year-old perimenopausal woman who underwent laparoscopic radical hysterectomy, bilateral salpingo-oophorectomy, total pelvic peritonectomy, pelvic lymphadenectomy to the mesenteric inferior artery, and omentectomy. Then, given the high probability of disease recurrence, the patient underwent a close follow-up consisting of positron emission tomography (PET)/computed tomography every 3 months and diagnostic (and if necessary operative) laparoscopy every 6 months. To date, the patient had 11 laparoscopies; 5 of them were preceded by a PET indicative of the presence of disease with high metabolic activity, which was confirmed at surgery and each time completely removed laparoscopically with no evidence of residual disease. To date, 5 years from diagnosis the patient is alive and continues her follow-up. Our report brings to light the ability of laparoscopic surgery to obtain disease control in a case of LMS with abdominal dissemination. Moreover, laparoscopic surgery, as demonstrated in our case, may have an important role in the close follow-up of the disease and allow a timely and early radical surgical approach of relapses before they become extremely large and difficult to remove radically.
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| http://dx.doi.org/10.1016/j.jmig.2016.05.005 | DOI Listing |
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