As Adams and Vanin (2016) have noted, different ways of funding long-term care (LTC) have different implications. Because health is not just healthcare, and LTC is not homogeneous, determining the appropriate public-private mix is complex. We suggest that how issues are framed helps influence policy choices, including who should pay for what, and how things should be financed. In addition, the distribution of expenditures for some services can be highly skewed, affecting the extent to which average cost data are useful in extrapolating their costs. We note that health expenditures fall into multiple categories, each presenting different policy issues. For example, framing LTC as health, as basic costs associated with living or as forced savings (like pensions) affects which funding approaches might be used, and the extent to which changes in the population distribution will affect cost structures. Underlying these discussions are questions of solidarity, and how much we believe that we are our brother's - or grandmother's - keeper.
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http://dx.doi.org/10.12927/hcpap.2016.24587 | DOI Listing |
Sci Rep
December 2024
Department of Civil Engineering, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.
Deep learning models are widely used for traffic forecasting on freeways due to their ability to learn complex temporal and spatial relationships. In particular, graph neural networks, which integrate graph theory into deep learning, have become popular for modeling traffic sensor networks. However, traditional graph convolutional networks (GCNs) face limitations in capturing long-range spatial correlations, which can hinder accurate long-term predictions.
View Article and Find Full Text PDFBAY 2413555 is a novel selective and reversible positive allosteric modulator of the type 2 muscarinic acetylcholine (M2) receptor, aimed at enhancing parasympathetic signaling and restoring cardiac autonomic balance for the treatment of heart failure (HF). This study tested the safety, tolerability and pharmacokinetics of this novel therapeutic option. REMOTE-HF was a multicenter, double-blind, randomized, placebo-controlled, phase Ib dose-titration study with two active arms.
View Article and Find Full Text PDFHere we report results of a phase 1 multi-institutional, open-label, dose-escalation trial (NCT02744287) of BPX-601, an investigational autologous PSCA-directed GoCAR-T® cell product containing an inducible MyD88/CD40 ON-switch responsive to the activating dimerizer rimiducid, in patients with metastatic pancreatic (mPDAC) or castration-resistant prostate cancer (mCRPC). Primary objectives were to evaluate safety and tolerability and determine the recommended phase 2 dose/schedule (RP2D). Secondary objectives included the assessment of efficacy and characterization of the pharmacokinetics of rimiducid.
View Article and Find Full Text PDFJ Adolesc
December 2024
Center for Legal Systems Research, RTI International, Research Triangle Park, North Carolina, USA.
Introduction: A growing body of research indicates that being incarcerated in an adult jail or prison as a juvenile can elevate one's exposure to adverse childhood experiences, including violent and sexual victimization and neglect, and may lead to several long-term difficulties. This study investigates the relationship between being confined in an adult jail or prison as a minor and experiencing violent victimization as an adult.
Methods: Data from the National Longitudinal Survey of Youth-1997 cohort were used in the study.
Cureus
November 2024
Intensive Care Unit, Hospital de Cascais, Lisboa, PRT.
Kawasaki disease (KD) is an inflammatory condition more common in children but rare in adults, where diagnosis can be challenging due to nonspecific symptoms. Early recognition is essential to prevent severe complications. We present the case of a 26-year-old male with adult-onset KD who initially presented with vague symptoms, resulting in diagnostic delays.
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