Acquired perforating dermatosis (APD) is an uncommon skin disorder seen in majority among patients with chronic kidney disease and also in those with diabetes mellitus. We present the clinicopathological features of APD in a 65-year-old patient with diabetes mellitus and end-stage kidney disease on hemodialysis and review the recent advances in the management of APD, as well as the mechanisms of transepidermal elimination of perforating dermatoses.
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