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Improving Emergency Medical Services (EMS) Care for People With Autism in the Prehospital Setting Through Sensory and Communication Aids.
Cureus
November 2024
Emergency Medicine, Franciscan Health Olympia Fields, Olympia Fields, USA.
Autism spectrum disorder (ASD) is a prevalent neurodevelopmental disorder characterized by social, communication, and behavioral challenges. Emergency medical services (EMS) environments, with their loud noises, bright lights, and unfamiliar personnel, often exacerbate these challenges, making care for individuals with ASD particularly complex. To address these challenges, the Franciscan Crown Point EMS system introduced the "Ben's Blue Bags" (BBBs) program.
View Article and Find Full Text PDFAn early-onset specific polygenic risk score optimizes age-based risk estimate and stratification of prostate cancer: population-based cohort study.
J Transl Med
April 2024
Department of Biostatistics, School of Public Health, Center for Global Health, Nanjing Medical University, Nanjing, China.
Article Synopsis
- Early-onset prostate cancer (EOPC), which affects men aged 55 or younger, presents a significant genetic risk and shows potential for early detection but typically results in poor prognoses.
- A study involving over 167,000 male participants aimed to develop age-specific polygenic risk scores (PRS) for personalized risk assessment and found that EOPC-PRS was strongly linked to EOPC risk compared to late-onset cases.
- The research highlighted that EOPC is more influenced by genetic factors like family history, while late-onset prostate cancer (LOPC) is more associated with environmental and lifestyle factors.
A profile of two different applicant test batteries with regards to sex and age in successful law enforcement applicants.
Work
April 2024
Faculty of Health Sciences and Medicine, Bond University, QLD, Australia.
Background: Law enforcement (LE) applicant assessments and initial academy training vary greatly across the United States of America (USA), with 820+ academies operating across 50 different states. Rising obesity and declining physical fitness underscore the need for benchmarks of applicant physical performance.
Objective: Create a "point-in-time" descriptive profile of the performance of LE applicants and determine any differences between males, females, and age using two applicant test batteries (ATBs).
Efficacy and safety of persimmon leaf formulated with green tea and sophora fruit extracts (BLH308) on hair growth: A randomized, double-blind, placebo-controlled clinical trial.
Skin Res Technol
September 2023
Department of Dermatology & Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, Republic of Korea.
Background: Recent research suggests that persimmon leaf extract (PLE) has an effect on inflammatory skin diseases. Previously, PLE is revealed to inhibit not only nitric oxide production but also inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) expression levels in mouse macrophages in vitro. Moreover, it significantly reduced IL-6 production and 5α-reductase expression in human follicle dermal papilla cells (HFDPCs).
View Article and Find Full Text PDFIntegrated multi-omics approach to distinct molecular characterization and classification of early-onset colorectal cancer.
Cell Rep Med
March 2023
Department of Environmental Genomics, Jiangsu Key Laboratory of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing Medical University, Nanjing, Jiangsu 211166, China; Department of Genetic Toxicology, The Key Laboratory of Modern Toxicology of Ministry of Education, Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, Jiangsu 211166, China; The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, Suzhou 215005, China. Electronic address:
Article Synopsis
- The incidence of early-onset colorectal cancer (EOCRC), diagnosed in individuals under 50, is rising, but its diverse causes are still not fully understood.
- Researchers analyzed genetic and molecular data from 79 Chinese EOCRC patients, supplemented by data from 126 additional subjects from international cohorts, revealing characteristics such as high mutation rates and significant DNA repair mechanisms.
- Findings highlighted that LMTK3 may play a key role in the development of EOCRC and could serve as a potential biomarker for targeted therapies, paving the way for advancements in precision oncology for colorectal cancer.
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