The design, synthesis, and evaluation of methyl 1,2,8,8a-tetrahydrocyclopropa[c]imidazolo[4,5-e]indol-4-one-6-carboxylate (CImI) derivatives are detailed representing analogs of duocarmycin SA and yatakemycin containing an imidazole replacement for the fused pyrrole found in the DNA alkylation subunit.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052114 | PMC |
| http://dx.doi.org/10.1016/j.bmc.2016.04.050 | DOI Listing |
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