[Acute intestinal obstruction revealing enteropathy associated t-cell lymphoma, about a case].

Pan Afr Med J

Service de Chirurgie Générale et Digestive B, Hôpital National de Zinder, Niger.

Published: January 2017

Enteropathy associated T-cell lymphoma (EATL) is a rare complication of celiac disease (CD). We report a case of EATL associated with CD revealed by acute intestinal obstruction. A North African woman of 38 years old with a history of infertility and chronic abdominal pain was admitted in emergency with acute intestinal obstruction. During the surgery, we found a tumor on the small intestine with mesenteric lymphadenopathy. Histology and immunohistochemistry of the specimen objectified a digestive T lymphoma CD3+ and immunological assessment of celiac disease was positive. The diagnosis of EATL was thus retained. Chemotherapy (CHOEP protocol) was established as well as gluten-free diet with a complete response to treatment. The EATL is a rare complication of CD that can be revealed by intestinal obstruction. The prognosis can be improved by early treatment involving surgery and chemotherapy. Its prevention requires early diagnosis of celiac and gluten-free diets.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4862778PMC
http://dx.doi.org/10.11604/pamj.2016.23.48.8909DOI Listing

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