Local protein synthesis directs growth cone turning of nascent axons, but mechanisms governing this process within compact, largely autonomous microenvironments remain poorly understood. In this issue, Wang et al. (2016. J. Cell Biol http://dx.doi.org/10.1083/jcb.201510107) demonstrate that the calcineurin regulator Down syndrome critical region 1 protein modulates both basal neurite outgrowth and growth cone turning.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878096 | PMC |
| http://dx.doi.org/10.1083/jcb.201605012 | DOI Listing |
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