Background: Primary chronic angle-closure glaucoma (PCACG) is one of the main types of glaucoma in China. Trabeculectomy is the most commonly used glaucoma filtration surgery for glaucoma in the world. Conventional trabeculectomy is prone to anesthesia-related complications intraoperative and operation-related complications postoperative in PCACG treatment. Modified minimally invasive trabeculectomy maybe can reduce the incidence of complications.
Methods: We conducted a prospective case series study and performed modified fornix-based trabeculectomy in 27 patients (30 eyes) under topical anesthesia; we then observed intraoperative anesthesia and cooperation effect, intraoperative and postoperative complications, preoperative and postoperative visual acuity, intraocular pressure (IOP), visual field, and the use of ocular hypotensive drugs. The patients were followed up for at least 12 months.
Results: All operations were completed successfully with no intraoperative complications. All 27 patients (30 eyes) were followed up for at least 12 months. No significant decrease in visual acuity was observed at days 1 or 7 and at months 1, 3, 6, and 12 after operation; however, a significant decrease in IOP was observed at days 1 and 7 and at months 1, 3, 6, and 12 after operation. Moreover, no significant progression in visual field mean defect was observed at month 12 after operation, and the number of ocular hypotensive drugs required was significantly reduced at months 6 and 12 after operation. By month 12 after operation, the overall success rate was 93.33% (28/30).
Conclusions: Modified minimally invasive trabeculectomy is safe and effective for the treatment of PCACG.
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Gynecol Oncol
January 2025
Department of Obstetrics, Gynaecology and Newborn Health, University of Melbourne and The Royal Women's Hospital, Melbourne, Victoria, Australia. Electronic address:
Objective: Women with BRCA1/2 pathogenic variants considering risk-reducing bilateral oophorectomy (RRSO) may be concerned about potential effects of surgical menopause on cognition. Whether RRSO affects cognition and whether hormone therapy (HT) modifies this effect remains uncertain. This study aimed to prospectively measure the effect of premenopausal RRSO on cognition and the modifying effects of HT up to 24 months.
View Article and Find Full Text PDFAnn Surg
January 2025
Amsterdam UMC, location University of Amsterdam, Department of Surgery, Amsterdam, the Netherlands.
Objective: To identify strategies to prevent and treat delayed gastric emptying (DGE) after pancreatic surgery.
Background: Among all complications of pancreatic surgery, DGE has the largest impact on prolonged hospital stay. Several randomized controlled trials (RCTs) have addressed DGE after pancreatic surgery, either as primary or as secondary outcome.
Acta Bioeng Biomech
June 2024
2Institute of Sound and Vibration Research, University of Southampton, United Kingdom.
Transmissibility is used to assess dynamic responses of the occupant-seat system, and most studies have exclusively assessed the transmissibility from the floor to the cushion or the backrest surface with the human body. In this investigation, the vertical vibration transmitted from the floor to six specific locations both on the seat surface and the frame when the seat was fixed on three positions on the track was examined utilizing an SAE J826 manikin and 12 male adults (0.25 to 20 Hz) for a duration of 120 seconds at three vibration amplitudes.
View Article and Find Full Text PDFJ Sci Food Agric
January 2025
Laboratorio de Investigación, Desarrollo y Evaluación de Alimentos (LIDEA), Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario (UNR), Santa Fe, Argentina.
Background: The antioxidant capacity of anthocyanins (AC) rapidly degrades during storage, highlighting the need for their stabilization. The conformational properties and high proline content of sodium caseinate (NaCAS), combined with the formation of NaCAS microgels in the presence of tara gum (TG) and acid gelation, suggest its potential as an effective stabilizing or encapsulating agent of AC.
Results: Spectrofluorimetric results suggest the formation of a complex between NaCAS and AC.
J Biomed Opt
January 2025
The Johns Hopkins University, Department of Biomedical Engineering, Baltimore, Maryland, United States.
Significance: Laparoscopic surgery presents challenges in localizing oncological margins due to poor contrast between healthy and malignant tissues. Optical properties can uniquely identify various tissue types and disease states with high sensitivity and specificity, making it a promising tool for surgical guidance. Although spatial frequency domain imaging (SFDI) effectively measures quantitative optical properties, its deployment in laparoscopy is challenging due to the constrained imaging environment.
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