The silent period evoked by the electrical stimulus of the abductor pollicis brevis and the triceps surae muscles was studied in both normal subjects and in patients affected by spinal compression, by multiple sclerosis and by familial degenerative myelopathy. In normal subjects, the duration of the silent period is shorter in the upper limbs than in the lower limbs. In patients with spinal compression and multiple sclerosis, the duration of the silent period in the lower limb is significantly greater. On the contrary, the duration in familial degenerative myelopathy is significantly longer, recording from the abductor pollicis brevis. The authors conclude that this technique is useful in the diagnosis of spinal lesions from compression and demyelination.
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Biomedicines
January 2025
Unidade Local de Saúde de Santo António, 4099-001 Porto, Portugal.
Glaucoma is one of the leading causes of permanent vision loss worldwide and has a profound impact on patients' quality of life. Vision impairment is strongly associated with several psychiatric disorders, like depression, anxiety, and sleep problems. These psychiatric issues are often exacerbated by the gradual, irreversible, and typically silent progression of the disease, contributing to increased mental health challenges for affected individuals.
View Article and Find Full Text PDFPLoS One
January 2025
Department of Disease Control, School of Veterinary, Medicine, University of Zambia Lusaka, Lusaka, Zambia.
Rift Valley fever (RVF) is an important viral zoonotic disease that not only affects ruminants but causes serious morbidity and mortality in humans. In humans, its symptoms range from mild flu-like signs to a severe form such as retinal damage, meningoencephalitis to haemorrhagic fever. In this study, 202 human serum samples were collected from central and western parts of Zambia and tested for RVF-specific antibodies using a commercially available ELISA kit.
View Article and Find Full Text PDFQ J Exp Psychol (Hove)
January 2025
Hearing Aid Laboratory, Northwestern University, Department of Communication Sciences and Disorders Evanston, IL, USA.
Listeners often find themselves in scenarios where speech is disrupted, misperceived, or otherwise difficult to recognize. In these situations, many individuals report exerting additional effort to understand speech, even when repairing speech may be difficult or impossible. This investigation aimed to characterize cognitive effort across time during both sentence listening and a post-sentence retention interval by observing the pupillary response of participants with normal to borderline normal hearing in response to two interrupted speech conditions: sentences interrupted by gaps of silence or bursts of noise.
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January 2025
Centre for Healthy Ageing, Health Futures Institute, Murdoch University, Perth, Australia.
Blood flow restriction (BFR) combined with low work rate exercise can enhance muscular and cardiovascular fitness. However, whether neural mechanisms mediate these enhancements remains unknown. This study examined changes in corticospinal excitability and motor cortical inhibition following arm cycle ergometry with and without BFR.
View Article and Find Full Text PDFSci Prog
January 2025
Virology Group, Vice-Chancellor of Research, Universidad El Bosque, Bogotá, Colombia.
Zika virus (ZIKV) is a flavivirus of significant epidemiological importance, utilizing various transmission strategies and infecting "immune privileged tissues" during both the pre- and postnatal periods. One such transmission method may involve extracellular vesicles (EVs). EVs can travel long distances without degrading, carrying complex messages that trigger different responses in recipient cells.
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